Declines in cervical cancer incidence among young women in the United States.

IF 7.2 1区 医学 Q1 ONCOLOGY
Sameer Vali Gopalani, Jin Qin, Manxia Wu, Virginia Senkomago
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引用次数: 0

Abstract

We calculated age-standardized cervical cancer incidence rates and trends by histologic type among women aged 15-29 years, using cancer registry data covering approximately 99% of the US population. We examined differences in incidence rates from the earliest to the most recent study period and quantified changes over time using joinpoint regression. Incidence rates for cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) decreased significantly during 1999-2022 in all age groups (15-20, 21-24, 25-29 years). Among women aged 15-20 years, cervical SCC rates were stable from 1999 to 2010 but declined substantially by 24.2% (95% confidence interval = -44.4 to -18.0) each year from 2010 to 2022, with only a few cases reported during 2017-2022. These findings show that cervical cancer incidence has declined among adolescents and young adult women in the United States, particularly in more recent years, highlighting the population-level impact of cervical cancer prevention measures.

美国年轻女性宫颈癌发病率的下降。
我们使用覆盖约99%美国人口的癌症登记数据,计算了15-29岁女性中按组织学类型划分的年龄标准化宫颈癌发病率和趋势。我们检查了从最早到最近的研究期间发病率的差异,并使用连接点回归量化了随时间的变化。1999-2022年期间,所有年龄组(15-20岁、21-24岁、25-29岁)的宫颈鳞状细胞癌(SCC)和腺癌(AC)发病率均显著下降。在15-20岁的女性中,1999-2010年宫颈鳞状细胞癌发病率稳定,但从2010-2022年每年大幅下降24.2% (95% CI -44.4, -18.0), 2017-2022年仅报告了少数病例。这些研究结果表明,美国青少年和年轻成年女性的宫颈癌发病率有所下降,特别是近年来,突出了宫颈癌预防措施对人口水平的影响。
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来源期刊
CiteScore
17.00
自引率
2.90%
发文量
203
审稿时长
4-8 weeks
期刊介绍: The Journal of the National Cancer Institute is a reputable publication that undergoes a peer-review process. It is available in both print (ISSN: 0027-8874) and online (ISSN: 1460-2105) formats, with 12 issues released annually. The journal's primary aim is to disseminate innovative and important discoveries in the field of cancer research, with specific emphasis on clinical, epidemiologic, behavioral, and health outcomes studies. Authors are encouraged to submit reviews, minireviews, and commentaries. The journal ensures that submitted manuscripts undergo a rigorous and expedited review to publish scientifically and medically significant findings in a timely manner.
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