Sameer Vali Gopalani, Jin Qin, Manxia Wu, Virginia Senkomago
{"title":"Declines in cervical cancer incidence among young women in the United States.","authors":"Sameer Vali Gopalani, Jin Qin, Manxia Wu, Virginia Senkomago","doi":"10.1093/jnci/djaf375","DOIUrl":null,"url":null,"abstract":"<p><p>We calculated age-standardized cervical cancer incidence rates and trends by histologic type among women aged 15-29 years, using cancer registry data covering approximately 99% of the US population. We examined differences in incidence rates from the earliest to the most recent study period and quantified changes over time using joinpoint regression. Incidence rates for cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) decreased significantly during 1999-2022 in all age groups (15-20, 21-24, 25-29 years). Among women aged 15-20 years, cervical SCC rates were stable from 1999 to 2010 but declined substantially by 24.2% (95% confidence interval = -44.4 to -18.0) each year from 2010 to 2022, with only a few cases reported during 2017-2022. These findings show that cervical cancer incidence has declined among adolescents and young adult women in the United States, particularly in more recent years, highlighting the population-level impact of cervical cancer prevention measures.</p>","PeriodicalId":14809,"journal":{"name":"JNCI Journal of the National Cancer Institute","volume":" ","pages":"941-946"},"PeriodicalIF":7.2000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108666/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JNCI Journal of the National Cancer Institute","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/jnci/djaf375","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
We calculated age-standardized cervical cancer incidence rates and trends by histologic type among women aged 15-29 years, using cancer registry data covering approximately 99% of the US population. We examined differences in incidence rates from the earliest to the most recent study period and quantified changes over time using joinpoint regression. Incidence rates for cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) decreased significantly during 1999-2022 in all age groups (15-20, 21-24, 25-29 years). Among women aged 15-20 years, cervical SCC rates were stable from 1999 to 2010 but declined substantially by 24.2% (95% confidence interval = -44.4 to -18.0) each year from 2010 to 2022, with only a few cases reported during 2017-2022. These findings show that cervical cancer incidence has declined among adolescents and young adult women in the United States, particularly in more recent years, highlighting the population-level impact of cervical cancer prevention measures.
期刊介绍:
The Journal of the National Cancer Institute is a reputable publication that undergoes a peer-review process. It is available in both print (ISSN: 0027-8874) and online (ISSN: 1460-2105) formats, with 12 issues released annually. The journal's primary aim is to disseminate innovative and important discoveries in the field of cancer research, with specific emphasis on clinical, epidemiologic, behavioral, and health outcomes studies. Authors are encouraged to submit reviews, minireviews, and commentaries. The journal ensures that submitted manuscripts undergo a rigorous and expedited review to publish scientifically and medically significant findings in a timely manner.