Jéssica Mulinari, Carolina Elisa Demaman Oro, Alessandra Cristina de Meneses, Guilherme Zin, Luciane Maria Colla, Marco Di Luccio, Rogério Marcos Dallago
{"title":"The development of active membranes: use of immobilized enzymes as fouling-reducing and self-cleaning agents.","authors":"Jéssica Mulinari, Carolina Elisa Demaman Oro, Alessandra Cristina de Meneses, Guilherme Zin, Luciane Maria Colla, Marco Di Luccio, Rogério Marcos Dallago","doi":"10.1080/07388551.2026.2639607","DOIUrl":null,"url":null,"abstract":"<p><p>Integrating of immobilized enzymes into membrane technology represents a significant advancement in the field of membrane science, particularly in addressing issues of fouling and self-cleaning. This review explores the development, techniques, and applications of enzymatic membranes, focusing on their fouling-degrading and self-cleaning properties. Enzymatic membranes combine catalytic and separation functions, offering environmentally friendly solutions with high selectivity and mild operating conditions. The review traces the historical development from early attempts in the 1970s using proteases in polymeric membranes to recent advancements involving a variety of enzymes and support materials. Various immobilization techniques, such as covalent bonding and physical adsorption, are discussed in relation to their impact on membrane performance. Applications span multiple industries, including food, biofuels, and wastewater treatment. Despite significant progress, the field continues to evolve with emerging technologies and novel enzyme immobilization strategies, presenting ongoing opportunities for research and industrial application.</p>","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"633-654"},"PeriodicalIF":8.7000,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Critical Reviews in Biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/07388551.2026.2639607","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/22 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Integrating of immobilized enzymes into membrane technology represents a significant advancement in the field of membrane science, particularly in addressing issues of fouling and self-cleaning. This review explores the development, techniques, and applications of enzymatic membranes, focusing on their fouling-degrading and self-cleaning properties. Enzymatic membranes combine catalytic and separation functions, offering environmentally friendly solutions with high selectivity and mild operating conditions. The review traces the historical development from early attempts in the 1970s using proteases in polymeric membranes to recent advancements involving a variety of enzymes and support materials. Various immobilization techniques, such as covalent bonding and physical adsorption, are discussed in relation to their impact on membrane performance. Applications span multiple industries, including food, biofuels, and wastewater treatment. Despite significant progress, the field continues to evolve with emerging technologies and novel enzyme immobilization strategies, presenting ongoing opportunities for research and industrial application.
期刊介绍:
Biotechnological techniques, from fermentation to genetic manipulation, have become increasingly relevant to the food and beverage, fuel production, chemical and pharmaceutical, and waste management industries. Consequently, academic as well as industrial institutions need to keep abreast of the concepts, data, and methodologies evolved by continuing research. This journal provides a forum of critical evaluation of recent and current publications and, periodically, for state-of-the-art reports from various geographic areas around the world. Contributing authors are recognized experts in their fields, and each article is reviewed by an objective expert to ensure accuracy and objectivity of the presentation.