Feasibility and Outcomes of a Robotic Retroperitoneal Approach to Para-Aortic Lymphadenectomy in Intermediate- and High-Risk Endometrial Cancer: A Prospective Study

IF 2.1 3区医学 Q2 SURGERY

International Journal of Medical Robotics and Computer Assisted Surgery Pub Date : 2026-03-20 DOI:10.1002/rcs.70148

Michiko Kubo-Kaneda, Kenta Yoshida, Saki Kotaka, Asumi Okumura, Tsuyoshi Mastumoto, Kota Okamoto, Eiji Kondo

{"title":"Feasibility and Outcomes of a Robotic Retroperitoneal Approach to Para-Aortic Lymphadenectomy in Intermediate- and High-Risk Endometrial Cancer: A Prospective Study","authors":"Michiko Kubo-Kaneda, Kenta Yoshida, Saki Kotaka, Asumi Okumura, Tsuyoshi Mastumoto, Kota Okamoto, Eiji Kondo","doi":"10.1002/rcs.70148","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>This prospective feasibility study evaluated the safety and efficacy of robotic retroperitoneal para-aortic lymphadenectomy in patients with intermediate-to high-risk endometrial cancer.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Patients with endometrial cancer who underwent robotic surgical staging at Mie University Hospital between October 2021 and May 2025 were prospectively enroled and analysed following ethics approval. Patient clinical data, intraoperative parameters, and postoperative quality of life (QOL) were collected according to a predefined protocol.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The study included 18 patients with a median operative time of 411.0 min, median blood loss of 51.0 mL, and 25.5 and 24.5 resected pelvic and para-aortic lymph nodes, respectively. Para-aortic lymph node metastasis was observed in one case, and postoperative complications in two. QOL returned to baseline within 28 days postoperatively.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The robotic retroperitoneal approach to para-aortic lymphadenectomy is a feasible and safe staging procedure for intermediate-to high-risk endometrial cancer, with rapid postoperative QOL recovery.</p>\n </section>\n \n <section>\n \n <h3> Trial Registration</h3>\n \n <p>This study was registered in the Japan Registry of Clinical Trials (jRCT1042210047).</p>\n </section>\n </div>","PeriodicalId":50311,"journal":{"name":"International Journal of Medical Robotics and Computer Assisted Surgery","volume":"22 2","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13003377/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Robotics and Computer Assisted Surgery","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/rcs.70148","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"SURGERY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

This prospective feasibility study evaluated the safety and efficacy of robotic retroperitoneal para-aortic lymphadenectomy in patients with intermediate-to high-risk endometrial cancer.

Methods

Patients with endometrial cancer who underwent robotic surgical staging at Mie University Hospital between October 2021 and May 2025 were prospectively enroled and analysed following ethics approval. Patient clinical data, intraoperative parameters, and postoperative quality of life (QOL) were collected according to a predefined protocol.

Results

The study included 18 patients with a median operative time of 411.0 min, median blood loss of 51.0 mL, and 25.5 and 24.5 resected pelvic and para-aortic lymph nodes, respectively. Para-aortic lymph node metastasis was observed in one case, and postoperative complications in two. QOL returned to baseline within 28 days postoperatively.

Conclusions

The robotic retroperitoneal approach to para-aortic lymphadenectomy is a feasible and safe staging procedure for intermediate-to high-risk endometrial cancer, with rapid postoperative QOL recovery.

Trial Registration

This study was registered in the Japan Registry of Clinical Trials (jRCT1042210047).

Abstract Image

查看原文本刊更多论文

一项前瞻性研究：机器人腹膜后入路行腹主动脉旁淋巴结切除术的可行性和结果。

背景：本前瞻性可行性研究评估了机器人腹膜后腹主动脉旁淋巴结切除术治疗中高风险子宫内膜癌患者的安全性和有效性。方法：前瞻性纳入2021年10月至2025年5月在Mie大学医院接受机器人手术分期的子宫内膜癌患者，并在伦理批准后进行分析。根据预先制定的方案收集患者临床资料、术中参数和术后生活质量（QOL）。结果：18例患者中位手术时间411.0 min，中位失血量51.0 mL，盆腔淋巴结切除25.5个，主动脉旁淋巴结切除24.5个。主动脉旁淋巴结转移1例，术后并发症2例。术后28天内生活质量恢复到基线水平。结论：机器人腹膜后入路行腹主动脉旁淋巴结切除术是一种可行且安全的中高危子宫内膜癌分期手术，术后生活质量恢复迅速。试验注册：本研究已在日本临床试验注册中心注册（jRCT1042210047）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Medical Robotics and Computer Assisted Surgery 医学-外科

CiteScore

4.50

自引率

12.00%

发文量

131

审稿时长

6-12 weeks

期刊介绍： The International Journal of Medical Robotics and Computer Assisted Surgery provides a cross-disciplinary platform for presenting the latest developments in robotics and computer assisted technologies for medical applications. The journal publishes cutting-edge papers and expert reviews, complemented by commentaries, correspondence and conference highlights that stimulate discussion and exchange of ideas. Areas of interest include robotic surgery aids and systems, operative planning tools, medical imaging and visualisation, simulation and navigation, virtual reality, intuitive command and control systems, haptics and sensor technologies. In addition to research and surgical planning studies, the journal welcomes papers detailing clinical trials and applications of computer-assisted workflows and robotic systems in neurosurgery, urology, paediatric, orthopaedic, craniofacial, cardiovascular, thoraco-abdominal, musculoskeletal and visceral surgery. Articles providing critical analysis of clinical trials, assessment of the benefits and risks of the application of these technologies, commenting on ease of use, or addressing surgical education and training issues are also encouraged. The journal aims to foster a community that encompasses medical practitioners, researchers, and engineers and computer scientists developing robotic systems and computational tools in academic and commercial environments, with the intention of promoting and developing these exciting areas of medical technology.