[On the question of the bioelement theory of aging.]

Abstract

The article presents the author's principles of the bioelement theory of aging, which considers the imbalance of essential macro- and microelements - so-called primary bioelements - as a key trigger for specific aging mechanisms. These elements perform structural, electrolytic, enzymatic, and other biochemical functions in the body. In the classification of bioelementome, primary simple bioelements include essential chemical elements in their simplest atomic or ionic forms. An imbalance of these bioelements disrupts metabolic homeostasis and thus serves as a trigger for numerous mechanisms of age-related dysfunction, including oxidative stress, proteostasis disruption, apoptosis, extracellular matrix damage, neurodegenerative processes, and other pathological transformations.