Variations of the ellipsoid method in estimating three-dimensional echocardiographic left atrial volume in dogs with myxomatous mitral valve disease: comparison with left atrial-to-aortic root ratios and planar volumetric methods.
B A Terhaar, C E Pelzek, S Siess, P F J Jennings, R Pariaut, W Hsue
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引用次数: 0
Abstract
Introduction/objectives: The ellipsoid method estimates left atrial (LA) volume using only linear diameters and may offer a practical volumetric alternative to the left atrial-to-aortic root ratio (LA/Ao). The aim of this study was to compare variations of the ellipsoid model with LA/Ao and planar volumetric methods, using real-time three-dimensional echocardiography (RT3D) as the reference standard.
Animals, materials, and methods: Seventy dogs with myxomatous mitral valve disease (43 stage B1, 17 stage B2, and 10 stages C/D) were prospectively imaged; 32 (17 stage B1, 10 stage B2, and five stages C/D) were re-imaged by another sonographer. In addition to long-axis and short-axis LA/Ao, body weight-indexed maximal LA volumes obtained using the spherical (right parasternal and left apical), monoplane ellipsoid (right parasternal and left apical), biplane ellipsoid, monoplane area-length and Simpson's method of discs (right parasternal and left apical), biplane area-length method and Simpson's method of discs, and real-time triplane methods were compared to those of RT3D.
Results: The LA/Ao methods showed the lowest correlation (Spearman's coefficient [rs] < 0.800). Based on concordance correlation coefficients (rc), the monoplane ellipsoid (right parasternal: rc = 0.901, left apical: rc = 0.924), biplane ellipsoid (rc = 0.947), biplane area-length (rc = 0.921), biplane Simpson's method of discs (rc = 0.947), and real-time triplane (rc = 0.972) volumetric methods demonstrated at least moderate agreement. However, only the left apical monoplane ellipsoid method exhibited no systematic bias (median of the differences [95% confidence interval]: 0.00 [-0.10 to 0.07]).
Study limitations: Reproducibility was assessed against a novice observer or measurer who was not involved in image acquisition.
Conclusion: The left apical monoplane ellipsoid method provides an effective linear option for estimating RT3D-derived maximum LA volume.
期刊介绍：
The mission of the Journal of Veterinary Cardiology is to publish peer-reviewed reports of the highest quality that promote greater understanding of cardiovascular disease, and enhance the health and well being of animals and humans. The Journal of Veterinary Cardiology publishes original contributions involving research and clinical practice that include prospective and retrospective studies, clinical trials, epidemiology, observational studies, and advances in applied and basic research.
The Journal invites submission of original manuscripts. Specific content areas of interest include heart failure, arrhythmias, congenital heart disease, cardiovascular medicine, surgery, hypertension, health outcomes research, diagnostic imaging, interventional techniques, genetics, molecular cardiology, and cardiovascular pathology, pharmacology, and toxicology.
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