Platelet transfusion guidelines for thrombocytopenic patients in non-surgical and non-traumatic care settings: A systematic review and methodological quality assessment

IF 7.2 2区医学 Q1 HEMATOLOGY

Blood Reviews Pub Date : 2026-07-01 Epub Date: 2026-03-10 DOI:10.1016/j.blre.2026.101388

Yana Criel, Hendrik B. Feys, Emmy De Buck, Philippe Vandekerckhove, Timothy Devos, Peter Vandenberghe, Hans Van Remoortel

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引用次数: 0

Abstract

This systematic review aimed to identify clinical practice guidelines (CPGs) for platelet transfusion in non-surgical and non-traumatic care settings, and appraise their methodological quality. We searched three databases and eight grey literature sources for CPGs published between 2015 and 2025. Methodological characteristics of the literature review and guideline development process were charted. Data on the targeted population, transfusion indication, and the direction and strength of the recommendations were extracted. CPG methodological quality was assessed using the AGREE II Rigour of Development domain. We identified 30 CPGs, including 89 recommendations. Platelet transfusion recommendations were summarized in interactive evidence maps. These tools can aid clinicians seeking evidence-based guidance to support clinical decision making, and highlight priorities for future research. AGREE II assessment indicated good to poor methodological quality of the included CPGs. This work underscores the importance of applying a rigorous and transparent methodology to ensure the development of reliable CPGs.

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血小板减少患者在非手术和非创伤性护理环境中的血小板输注指南：系统回顾和方法学质量评估。

本系统综述旨在确定在非手术和非创伤性护理环境中血小板输注的临床实践指南（CPGs），并评估其方法学质量。我们检索了3个数据库和8个灰色文献来源，检索了2015年至2025年间发表的cpg。文献综述的方法学特征和指南制定过程被绘制成图表。提取了有关目标人群、输血指征以及建议的方向和力度的数据。CPG方法的质量是使用开发领域的AGREE II严谨性来评估的。我们确定了30个cpg，包括89个推荐。在交互式证据图中总结了血小板输注建议。这些工具可以帮助临床医生寻求基于证据的指导，以支持临床决策，并突出未来研究的重点。AGREE II评估表明纳入的cpg的方法学质量从好到差。这项工作强调了采用严格和透明的方法来确保制定可靠的CPGs的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood Reviews 医学-血液学

CiteScore

13.80

自引率

1.40%

发文量

期刊介绍： Blood Reviews, a highly regarded international journal, serves as a vital information hub, offering comprehensive evaluations of clinical practices and research insights from esteemed experts. Specially commissioned, peer-reviewed articles authored by leading researchers and practitioners ensure extensive global coverage across all sub-specialties of hematology.