{"title":"Digital Cognitive Assessment for Older Adults: Validation of an Automated Three-Module Tool for Mild Cognitive Impairment and Dementia Screening.","authors":"Dong-Ni Pan, Hailun Xie, Juejing Ren, Ji Shen, Jing Li, Yanjia Zeng, Wen Wang, Dingyao Fan, Gui Xue","doi":"10.1159/000549530","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>With the aging global population, effective screening tools for age-related cognitive disorders are urgently needed. Mild cognitive impairment (MCI), a transitional stage between normal aging and dementia, requires early detection for timely intervention.</p><p><strong>Methods: </strong>The current research developed an innovative electronic assessment tool designed with three task modules targeting executive function, memory binding, and spatial navigation to quickly screen for MCI in older adults. A validation study was conducted with 271 older participants, aged 56 to 89, comprising 138 individuals with MCI and 133 cognitively normal controls. An independent dataset from a community hospital was used for further confirmation.</p><p><strong>Results: </strong>The validation study indicated excellent reliability and validity, achieving 72% accuracy in distinguishing MCI from cognitively normal individuals, with excellent screening power (AUC = 0.807; 95% CI: 0.756-0.858). This performance surpasses that of the paper-and-pencil Mini-Mental State Examination (MMSE). The independent dataset from a community hospital further confirmed that the tool achieved a good accuracy rate of 93% (26/28) in predicting MCI.</p><p><strong>Conclusion: </strong>These results provide strong tool support for the early identification of MCI, enhancing the effective management of cognitive decline in at-risk elderly individuals.</p>","PeriodicalId":11126,"journal":{"name":"Dementia and Geriatric Cognitive Disorders","volume":" ","pages":"1-17"},"PeriodicalIF":2.5000,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dementia and Geriatric Cognitive Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000549530","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: With the aging global population, effective screening tools for age-related cognitive disorders are urgently needed. Mild cognitive impairment (MCI), a transitional stage between normal aging and dementia, requires early detection for timely intervention.
Methods: The current research developed an innovative electronic assessment tool designed with three task modules targeting executive function, memory binding, and spatial navigation to quickly screen for MCI in older adults. A validation study was conducted with 271 older participants, aged 56 to 89, comprising 138 individuals with MCI and 133 cognitively normal controls. An independent dataset from a community hospital was used for further confirmation.
Results: The validation study indicated excellent reliability and validity, achieving 72% accuracy in distinguishing MCI from cognitively normal individuals, with excellent screening power (AUC = 0.807; 95% CI: 0.756-0.858). This performance surpasses that of the paper-and-pencil Mini-Mental State Examination (MMSE). The independent dataset from a community hospital further confirmed that the tool achieved a good accuracy rate of 93% (26/28) in predicting MCI.
Conclusion: These results provide strong tool support for the early identification of MCI, enhancing the effective management of cognitive decline in at-risk elderly individuals.
期刊介绍:
As a unique forum devoted exclusively to the study of cognitive dysfunction, ''Dementia and Geriatric Cognitive Disorders'' concentrates on Alzheimer’s and Parkinson’s disease, Huntington’s chorea and other neurodegenerative diseases. The journal draws from diverse related research disciplines such as psychogeriatrics, neuropsychology, clinical neurology, morphology, physiology, genetic molecular biology, pathology, biochemistry, immunology, pharmacology and pharmaceutics. Strong emphasis is placed on the publication of research findings from animal studies which are complemented by clinical and therapeutic experience to give an overall appreciation of the field.