{"title":"Use of cryobiopsy for diagnosis and treatment of a rare laryngeal tumor in pediatrics.","authors":"Rubén Ferraz, Cintia Antonioli, Ivanna Boalichuk","doi":"10.5546/aap.2025-10901.eng","DOIUrl":null,"url":null,"abstract":"<p><p>This report highlights the importance of differential diagnosis of laryngeal obstructive airway pathologies, as well as the growing value of endoscopic techniques, such as cryobiopsy, in achieving a definitive, accurate diagnosis. This is an 8-month-old infant who presented with signs of airway obstruction and a history consistent with foreign body aspiration. During endoscopy under general anesthesia, a supraglottic tumor was observed, which was resected using a cryobiopsy probe, a method that is not widely used in pediatrics and in our setting. Postoperative pathological anatomy confirmed the diagnosis of juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis with an uncommon location in the larynx.</p>","PeriodicalId":8338,"journal":{"name":"Archivos argentinos de pediatria","volume":" ","pages":"e202510901"},"PeriodicalIF":0.5000,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos argentinos de pediatria","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5546/aap.2025-10901.eng","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
This report highlights the importance of differential diagnosis of laryngeal obstructive airway pathologies, as well as the growing value of endoscopic techniques, such as cryobiopsy, in achieving a definitive, accurate diagnosis. This is an 8-month-old infant who presented with signs of airway obstruction and a history consistent with foreign body aspiration. During endoscopy under general anesthesia, a supraglottic tumor was observed, which was resected using a cryobiopsy probe, a method that is not widely used in pediatrics and in our setting. Postoperative pathological anatomy confirmed the diagnosis of juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis with an uncommon location in the larynx.
期刊介绍:
Archivos Argentinos de Pediatría is the official publication of the Sociedad Argentina de Pediatría (SAP) and has been published without interruption since 1930. Its publication is bimonthly.
Archivos Argentinos de Pediatría publishes articles related to perinatal, child and adolescent health and other relevant disciplines for the medical profession.