{"title":"Optimization of crystalline lens refractive index to improve the accuracy of intraocular lens power calculation in patients with dense cataract.","authors":"Tsuyoshi Nogami, Takashi Kojima, Akeno Tamaoki, Ayako Sawaki, Asato Hasegawa, Tatsushi Kaga","doi":"10.1097/j.jcrs.0000000000001941","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate effects of crystalline lens refractive index (LRI) on prediction error (PE) and suggest the optimal LRI in cases of dense cataract.</p><p><strong>Setting: </strong>Chukyo Hospital, Aichi, Japan.</p><p><strong>Design: </strong>Retrospective consecutive case series study.</p><p><strong>Methods: </strong>Patients who underwent cataract surgery were enrolled and allocated into Group A (nuclear hardness ≤III) and B (nuclear hardness ≥IV) based on the Emery-Little classification. The swept-source optical biometer was used for biometric measurements. Assuming the postoperative axial length (AL) to be the valid value, a corrected LRI (CLRI) was calculated to make the preoperative AL equivalent to the postoperative one. In the validation group, the PE of the SRK/T formula and Barrett Universal II (BUII) were evaluated using the precorrection and postcorrection refractive indices.</p><p><strong>Results: </strong>Of the 5196 enrolled eyes, 1084 were evaluated. In Group A, there was no significant difference between the preoperative and postoperative ALs ( P = .07). In Group B, the mean postoperative AL (24.09 ± 2.05 mm) was significantly shorter than the mean preoperative AL (24.12 ± 2.06 mm) ( P < .001). The average CLRI in Group A and B were 1.41 and 1.42, respectively. In the validation group, the PEs using CLRI (SRK/T, 0.10 ± 0.48 diopters [D]; BUII, 0.03 ± 0.35 D) were significantly smaller than those using LRI (SRK/T, 0.18 ± 0.49 D; BUII, 0.12 ± 0.36 D) ( P < .001).</p><p><strong>Conclusions: </strong>In cases of high lens nucleus hardness, the use of proposed CLRI demonstrated potentials for reducing PE.</p>","PeriodicalId":15214,"journal":{"name":"Journal of cataract and refractive surgery","volume":" ","pages":"890-896"},"PeriodicalIF":3.7000,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cataract and refractive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/j.jcrs.0000000000001941","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To evaluate effects of crystalline lens refractive index (LRI) on prediction error (PE) and suggest the optimal LRI in cases of dense cataract.
Setting: Chukyo Hospital, Aichi, Japan.
Design: Retrospective consecutive case series study.
Methods: Patients who underwent cataract surgery were enrolled and allocated into Group A (nuclear hardness ≤III) and B (nuclear hardness ≥IV) based on the Emery-Little classification. The swept-source optical biometer was used for biometric measurements. Assuming the postoperative axial length (AL) to be the valid value, a corrected LRI (CLRI) was calculated to make the preoperative AL equivalent to the postoperative one. In the validation group, the PE of the SRK/T formula and Barrett Universal II (BUII) were evaluated using the precorrection and postcorrection refractive indices.
Results: Of the 5196 enrolled eyes, 1084 were evaluated. In Group A, there was no significant difference between the preoperative and postoperative ALs ( P = .07). In Group B, the mean postoperative AL (24.09 ± 2.05 mm) was significantly shorter than the mean preoperative AL (24.12 ± 2.06 mm) ( P < .001). The average CLRI in Group A and B were 1.41 and 1.42, respectively. In the validation group, the PEs using CLRI (SRK/T, 0.10 ± 0.48 diopters [D]; BUII, 0.03 ± 0.35 D) were significantly smaller than those using LRI (SRK/T, 0.18 ± 0.49 D; BUII, 0.12 ± 0.36 D) ( P < .001).
Conclusions: In cases of high lens nucleus hardness, the use of proposed CLRI demonstrated potentials for reducing PE.
期刊介绍:
The Journal of Cataract & Refractive Surgery (JCRS), a preeminent peer-reviewed monthly ophthalmology publication, is the official journal of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS).
JCRS publishes high quality articles on all aspects of anterior segment surgery. In addition to original clinical studies, the journal features a consultation section, practical techniques, important cases, and reviews as well as basic science articles.