Primary diffuse large B-cell lymphoma of cauda equina: a rare and challenging diagnosis.

IF 0.6 4区医学 Q4 HEMATOLOGY

Journal of Hematopathology Pub Date : 2026-03-14 DOI:10.1007/s12308-026-00689-3

Tamara Pikivaca, Mark A Rudolf, Anamarija M Perry

引用次数: 0

Abstract

Primary diffuse large B-cell lymphoma (DLBCL) of cauda equina is a very rare manifestation of neurolymphomatosis. A 52-year-old female presented with progressive symptoms of left lower extremity burning sensation. After initial conservative management with no improvement, MRI of the lumbosacral spine showed pathologic enhancement and thickening of cauda equina nerve roots. Examination of cerebrospinal fluid, coupled with flow cytometry, was diagnostic of DLBCL. Clinicians and pathologists should be aware of this unusual and challenging clinical presentation of DLBCL.

查看原文本刊更多论文

马尾原发性弥漫性大b细胞淋巴瘤：罕见且具有挑战性的诊断。

原发性弥漫性大b细胞淋巴瘤（DLBCL）是一种非常罕见的神经淋巴瘤。52岁女性，表现为左下肢烧灼感进行性症状。在最初的保守治疗没有改善后，腰骶棘MRI显示病理性增强和马尾神经根增厚。脑脊液检查结合流式细胞术可诊断为DLBCL。临床医生和病理学家应该意识到DLBCL的这种不寻常和具有挑战性的临床表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Hematopathology HEMATOLOGYPATHOLOGY-PATHOLOGY

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Journal of Hematopathology aims at providing pathologists with a special interest in hematopathology with all the information needed to perform modern pathology in evaluating lymphoid tissues and bone marrow. To this end the journal publishes reviews, editorials, comments, original papers, guidelines and protocols, papers on ancillary techniques, and occasional case reports in the fields of the pathology, molecular biology, and clinical features of diseases of the hematopoietic system. The journal is the unique reference point for all pathologists with an interest in hematopathology. Molecular biologists involved in the expanding field of molecular diagnostics and research on lymphomas and leukemia benefit from the journal, too. Furthermore, the journal is of major interest for hematologists dealing with patients suffering from lymphomas, leukemias, and other diseases. The journal is unique in its true international character. Especially in the field of hematopathology it is clear that there are huge geographical variations in incidence of diseases. This is not only locally relevant, but due to globalization, relevant for all those involved in the management of patients.