The genomic model P-CARE enables precision prostate cancer screening in a national healthcare system

IF 28.5 1区医学 Q1 ONCOLOGY

Nature cancer Pub Date : 2026-03-13 DOI:10.1038/s43018-025-01111-0

引用次数: 0

Abstract

We developed and clinically implemented the genomic prostate cancer risk prediction model P-CARE that identifies men at a high or low risk of prostate cancer. P-CARE enabled the design and initiation of a precision screening trial across the national healthcare system in which it was developed.

Abstract Image

查看原文本刊更多论文

基因组模型P-CARE能够在国家医疗保健系统中进行精确的前列腺癌筛查。

我们开发并临床实施了基因组前列腺癌风险预测模型P-CARE，该模型可识别前列腺癌高风险或低风险的男性。P-CARE使设计和启动整个国家医疗保健系统的精确筛选试验成为可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature cancer Medicine-Oncology

CiteScore

31.10

自引率

1.80%

发文量

129

期刊介绍： Cancer is a devastating disease responsible for millions of deaths worldwide. However, many of these deaths could be prevented with improved prevention and treatment strategies. To achieve this, it is crucial to focus on accurate diagnosis, effective treatment methods, and understanding the socioeconomic factors that influence cancer rates. Nature Cancer aims to serve as a unique platform for sharing the latest advancements in cancer research across various scientific fields, encompassing life sciences, physical sciences, applied sciences, and social sciences. The journal is particularly interested in fundamental research that enhances our understanding of tumor development and progression, as well as research that translates this knowledge into clinical applications through innovative diagnostic and therapeutic approaches. Additionally, Nature Cancer welcomes clinical studies that inform cancer diagnosis, treatment, and prevention, along with contributions exploring the societal impact of cancer on a global scale. In addition to publishing original research, Nature Cancer will feature Comments, Reviews, News & Views, Features, and Correspondence that hold significant value for the diverse field of cancer research.