Placement Error and Bone Regeneration of Customized Titanium Mesh With Vacuum-Formed Placing Template for Anterior Maxillary Bone Defects: A Retrospective Case Series Study

IF 5.9 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Oral Implants Research Pub Date : 2026-06-04 Epub Date: 2026-03-13 DOI:10.1111/clr.70115

Shunhao Zhang, Mi Zhou, Yuxuan Zhao, Wen Chen, Xiaoxiao Cai

{"title":"Placement Error and Bone Regeneration of Customized Titanium Mesh With Vacuum-Formed Placing Template for Anterior Maxillary Bone Defects: A Retrospective Case Series Study","authors":"Shunhao Zhang, Mi Zhou, Yuxuan Zhao, Wen Chen, Xiaoxiao Cai","doi":"10.1111/clr.70115","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To evaluate placement error, bone regeneration, and mesh exposure of three-dimensionally printed customized titanium mesh (3DPC Ti-mesh) guided by a vacuum-formed placing template in guided bone regeneration (GBR) for anterior maxillary defects.</p>\n </section>\n \n <section>\n \n <h3> Material and Methods</h3>\n \n <p>10 patients (23 implants) with Terheyden 2/4 or 3/4 defects were included. CBCT data of pre-operation (T0), immediate post-operation (T2), and 5–8 months post-operation (T3) were reconstructed. These three models and preoperative design (T1) model were co-registered to a common coordinate system. Mesh displacement and contour discrepancy were measured. Bone regeneration was evaluated in terms of bone volume and implant-related bone height and width. Classification, time, and rate of mesh exposures were recorded.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Ti-mesh exhibited 0.57 ± 0.65 mm buccal displacement from T1 to T2 and 0.58 ± 0.57 mm apical displacement from T2 to T3. Mesh contour discrepancy was 0.70 ± 0.20 mm between T1 and T2 and decreased to 0.37 ± 0.12 mm between T2 and T3. Comparing T2 to T1, graft volume accuracy reached 91.1% ± 7.6%. Non-infected mesh exposure occurred in 26% implant sites. From T2 to T3, vertical bone resorption of 1.69 ± 1.56 mm and 0.14 ± 0.63 mm were recorded in exposed and non-exposed groups, respectively.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>To our knowledge, this is the first study to validate the use of a vacuum-formed template for positioning 3DPC Ti-mesh. Within the study limitations, this technique is a feasible approach for placing customized mesh in anterior maxillary GBR.</p>\n </section>\n </div>","PeriodicalId":10455,"journal":{"name":"Clinical Oral Implants Research","volume":"37 6","pages":"731-746"},"PeriodicalIF":5.9000,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Oral Implants Research","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/clr.70115","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/13 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives

To evaluate placement error, bone regeneration, and mesh exposure of three-dimensionally printed customized titanium mesh (3DPC Ti-mesh) guided by a vacuum-formed placing template in guided bone regeneration (GBR) for anterior maxillary defects.

Material and Methods

10 patients (23 implants) with Terheyden 2/4 or 3/4 defects were included. CBCT data of pre-operation (T0), immediate post-operation (T2), and 5–8 months post-operation (T3) were reconstructed. These three models and preoperative design (T1) model were co-registered to a common coordinate system. Mesh displacement and contour discrepancy were measured. Bone regeneration was evaluated in terms of bone volume and implant-related bone height and width. Classification, time, and rate of mesh exposures were recorded.

Results

Ti-mesh exhibited 0.57 ± 0.65 mm buccal displacement from T1 to T2 and 0.58 ± 0.57 mm apical displacement from T2 to T3. Mesh contour discrepancy was 0.70 ± 0.20 mm between T1 and T2 and decreased to 0.37 ± 0.12 mm between T2 and T3. Comparing T2 to T1, graft volume accuracy reached 91.1% ± 7.6%. Non-infected mesh exposure occurred in 26% implant sites. From T2 to T3, vertical bone resorption of 1.69 ± 1.56 mm and 0.14 ± 0.63 mm were recorded in exposed and non-exposed groups, respectively.

Conclusions

To our knowledge, this is the first study to validate the use of a vacuum-formed template for positioning 3DPC Ti-mesh. Within the study limitations, this technique is a feasible approach for placing customized mesh in anterior maxillary GBR.

查看原文本刊更多论文

上颌前骨缺损定制钛网真空成形放置模板放置误差与骨再生：回顾性病例系列研究。

目的评价真空成型放置模板引导下三维打印定制钛网（3DPC Ti-mesh）在上颌前牙缺损引导骨再生（GBR）中的放置误差、骨再生和补片暴露情况。材料与方法选取Terheyden 2/4或3/4缺损患者10例（23例）。重建术前（T0）、术后即刻（T2）、术后5-8个月（T3） CBCT数据。这三个模型与术前设计（T1）模型共同配准到一个共同的坐标系。测量网格位移和轮廓差。根据骨体积和种植体相关的骨高度和骨宽度来评估骨再生。记录分类、时间和网片曝光率。结果从T1到T2， sti -mesh的口腔位移为0.57±0.65 mm，从T2到T3的根尖位移为0.58±0.57 mm。T1与T2之间的网格轮廓差为0.70±0.20 mm， T2与T3之间的网格轮廓差为0.37±0.12 mm。T2与T1相比，移植物体积精度达到91.1%±7.6%。26%的植入部位出现未感染的补片暴露。T2 ~ T3暴露组和未暴露组垂直骨吸收分别为1.69±1.56 mm和0.14±0.63 mm。据我们所知，这是第一次验证使用真空成型模板定位3DPC Ti-mesh的研究。在研究的限制下，该技术是上颌前牙GBR放置定制补片的可行方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Oral Implants Research 医学-工程：生物医学

CiteScore

7.70

自引率

11.60%

发文量

149

审稿时长

3 months

期刊介绍： Clinical Oral Implants Research conveys scientific progress in the field of implant dentistry and its related areas to clinicians, teachers and researchers concerned with the application of this information for the benefit of patients in need of oral implants. The journal addresses itself to clinicians, general practitioners, periodontists, oral and maxillofacial surgeons and prosthodontists, as well as to teachers, academicians and scholars involved in the education of professionals and in the scientific promotion of the field of implant dentistry.