Impact of Neighborhood and Individual Social Drivers of Health on Outcomes Following Congenital Heart Surgery.

Andrew Well, Heather Van Diest, Brett R Anderson, Wei Zhang, Kathleen Carberry, Alexandra Lamari-Fisher, Jeremy T Affolter, Erin A Gottlieb, Jeffery P Jacobs, Charles D Fraser, Carlos M Mery
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Abstract

BackgroundDespite advances in congenital heart surgery (CHS) and improvements in outcomes, disparities continue to exist. Social Drivers of Health (SDoH) have been associated with many aspects of health and wellness including congenital heart disease. The goal was to evaluate the impact of individual and neighborhood-level SDoH on outcomes following CHS.MethodsRetrospective review of the Society of Thoracic Surgeons Congenital Heart Surgery Database from 2014 to 2022 linked via ZIP code with the Centers for Disease Control and Prevention Social Vulnerability Index (SVI). ZIP codes were ranked by their SVI score with the first quintile the least vulnerable and the fifth the most vulnerable. The primary outcome was STS perioperative mortality.ResultsA total of 49 centers with ≥85% ZIP code completion rate were included. Those with missing ZIP codes (n = 1329) or missing data (n = 5651) were excluded resulting in a final cohort of 16,238 (69.5%, 11,285/16,238) cases. Of the final cohort, 8,977/16,238 (55.3%) were Non-Hispanic White and 7084/16,238 (43.6%) had private insurance. There were 448/16,238 (2.8%) STS perioperative mortalities. In the fully adjusted model, individual Non-Hispanic Black race (OR:1.76 [95% CI: 1.20-2.52]), Non-Hispanic Other race (OR: 2.39 [95% CI: 1.10-4.99]), Medicaid (OR:1.55 [95% CI: 1.04-2.30]), None/Self/Charity Insurance (OR:2.60 [95% CI: 1.09-5.93]), as well as increasing SVI quintile with SVI2 (OR: 1.22 [95% CI: 0.86-1.75]), SVI3 (OR: 1.71 [95% CI: 1.07-2.73]), SVI4 (OR: 1.92 [95% CI: 1.04-3.53]) and SVI5 (OR: 3.09 [95% CI: 1.36-6.87]), had increased odds of STS perioperative mortality.ConclusionsAfter adjusting for clinical characteristics, both individual and neighborhood Social Drivers of Health conferred increased odds of perioperative mortality following CHS. These results spotlight the disparities driven by individual circumstances beyond clinical characteristics and reinforce the need to intervene at both the individual and community levels to improve outcomes.

邻里和个人社会健康驱动因素对先天性心脏手术后预后的影响
背景:尽管先天性心脏手术(CHS)取得了进步,结果也有所改善,但差距仍然存在。健康的社会驱动因素(SDoH)与健康和保健的许多方面有关,包括先天性心脏病。目的是评估个人和社区水平的SDoH对CHS后结果的影响。方法回顾性分析2014 - 2022年胸外科学会先天性心脏外科数据库,通过邮政编码与疾病控制与预防中心的社会脆弱性指数(SVI)联系。邮政编码按照SVI得分进行排名,前五分之一是最不脆弱的,第五分之一是最脆弱的。主要结局为STS围手术期死亡率。结果共纳入49个邮编完成率≥85%的中心。排除邮政编码缺失(n = 1329)或数据缺失(n = 5651)的患者,最终队列为16,238例(69.5%,11,285/16,238)。在最后的队列中,8,977/16,238(55.3%)是非西班牙裔白人,7084/16,238(43.6%)有私人保险。STS围手术期死亡率为448/ 16238(2.8%)。在完全调整后的模型中,个体非西班牙裔黑人(OR:1.76 [95% CI: 1.20-2.52])、非西班牙裔其他种族(OR: 2.39 [95% CI: 1.10-4.99])、医疗补助(OR:1.55 [95% CI: 1.04-2.30])、无/自我/慈善保险(OR:2.60 [95% CI: 1.09-5.93])以及SVI五分位数增加的SVI2 (OR: 1.22 [95% CI: 0.86-1.75])、SVI3 (OR: 1.71 [95% CI: 1.07-2.73])、SVI4 (OR: 1.92 [95% CI: 1.04-3.53])和SVI5 (OR: 3.09 [95% CI: 1.36-6.87])增加了STS围手术期死亡率。结论:在调整临床特征后,个体和社区社会健康驱动因素均增加了CHS围手术期死亡率。这些结果突出了临床特征以外的个人情况造成的差异,并加强了在个人和社区层面进行干预以改善结果的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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