Strategies to Improve Detection of Novel Pandemic Pathogens: Cost Versus Detection Performance for Promising Pathogen-Agnostic Detection Workflows.

Rand health quarterly Pub Date : 2026-03-30 eCollection Date: 2026-03-01
Alex Demarsh, Pedro Nascimento de Lima, Cassidy Nelson, Javier Rojas Aguilera, Nathan Duarte, Sella Nevo, Henry H Willis
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Abstract

This RAND analysis compares three pathogen-agnostic biosurveillance strategies-syndromic, wearable, and environmental-using modeling to assess cost versus detection performance. Environmental sampling detected outbreaks fastest, followed by wearable sensors, although both lost advantage with highly transmissible or symptomatic diseases. Limited pilot deployments could refine real-world costs and validate early-warning performance.

改进新型大流行病原体检测的策略:成本与有前途的病原体不可知检测工作流程的检测性能。
这份兰德分析比较了三种病原体不可知的生物监测策略——综合征、可穿戴和环境——使用建模来评估成本与检测性能。环境采样检测到疫情的速度最快,其次是可穿戴传感器,尽管两者在高传染性或有症状的疾病中都失去了优势。有限的试点部署可以改善现实世界的成本,并验证早期预警的性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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