Autism and immigration background, insights from a population-based study.

IF 2.5 4区医学 Q2 PEDIATRICS

Paediatrics & child health Pub Date : 2025-12-12 eCollection Date: 2026-03-01 DOI:10.1093/pch/pxaf115

M Florencia Ricci, Gilles R Detillieux, Sepideh Yousefiasl, Lonnie Zwaigenbaum, Stefanie Narvey, Marina Yogendran, Marcelo L Urquia

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引用次数: 0

Abstract

Objectives: To examine the relationship between immigration and autism in Manitoba, Canada, using population-based data.

Methods: We linked Manitoba's Rehabilitation Centre for Children clinical registry (May 2016-December 2022), the province's primary and only publicly funded autism evaluation site for children ≤6 years, with an official immigration registry. We estimated incidence of autism and adjusted relative risks (aRR) with 95% confidence intervals (CI) across subgroups defined by child and parent immigration status.

Results: A total of 217,811 children aged 18 months to 6 years resided in Manitoba during the study period and met inclusion criteria. Among 2408 children diagnosed with autism, 1136 (47%) had at least one immigrant parent. Compared with Canadian-born children of nonimmigrant parents, autism risk was highest among Canadian-born children of at least one immigrant parent (aRR: 2.29; 95% CI: 2.09-2.51), followed by immigrant children of at least one immigrant parent (aRR: 1.72; 95% CI: 1.42-2.09). Maternal length of stay in Canada and refugee status was not associated with autism risk. In secondary analysis examining parental contribution to likelihood of autism, compared with Canadian children of two nonimmigrant parents, likelihood of autism diagnosis was higher among children in all parental immigration categories, but highest when both the mother and the father were immigrants (aRR: 3.08, 95% CI: 2.62-3.62).

Conclusion: Children of immigrant families in Manitoba had higher rates of autism. Additional studies are warranted to assess whether similar results occur in other Canadian jurisdictions, and to investigate possible underlying factors behind this association.

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自闭症和移民背景，来自一项基于人群的研究的见解。

目的：利用基于人口的数据，研究加拿大马尼托巴省移民与自闭症之间的关系。方法：我们将马尼托巴儿童康复中心临床登记（2016年5月至2022年12月）与官方移民登记相关联，该中心是该省主要且唯一由政府资助的6岁以下儿童自闭症评估网站。我们估计了自闭症的发病率，并以95%的置信区间（CI）调整了由儿童和父母移民身份定义的亚组的相对风险（aRR）。结果：共有217,811名18个月至6岁的儿童在研究期间居住在曼尼托巴，符合纳入标准。在2408名被诊断为自闭症的儿童中，1136名（47%）至少有一位移民父母。与非移民父母的加拿大出生的孩子相比，至少有一位移民父母的加拿大出生的孩子患自闭症的风险最高（aRR: 2.29; 95% CI: 2.09-2.51），其次是至少有一位移民父母的移民孩子（aRR: 1.72; 95% CI: 1.42-2.09）。母亲在加拿大的停留时间和难民身份与自闭症风险无关。在检查父母对自闭症可能性贡献的二次分析中，与两名非移民父母的加拿大儿童相比，所有父母移民类别的儿童中自闭症诊断的可能性更高，但当母亲和父亲都是移民时，自闭症诊断的可能性最高（aRR: 3.08, 95% CI: 2.62-3.62）。结论：马尼托巴省移民家庭的孩子患自闭症的比例更高。需要进一步的研究来评估类似的结果是否发生在加拿大其他司法管辖区，并调查这种关联背后可能的潜在因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Paediatrics & child health 医学-小儿科

CiteScore

2.10

自引率

5.30%

发文量

208

审稿时长

>12 weeks

期刊介绍： Paediatrics & Child Health (PCH) is the official journal of the Canadian Paediatric Society, and the only peer-reviewed paediatric journal in Canada. Its mission is to advocate for the health and well-being of all Canadian children and youth and to educate child and youth health professionals across the country. PCH reaches 8,000 paediatricians, family physicians and other child and youth health professionals, as well as ministers and officials in various levels of government who are involved with child and youth health policy in Canada.