Possible Association Between Retinal Arterial Occlusions and Subretinal Drusenoid Deposits: A Missing Link.

IF 1.1 4区 医学 Q4 OPHTHALMOLOGY
Dmitrii S Maltsev, Alexei N Kulikov, Yana A Kalinicheva
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引用次数: 0

Abstract

Background and objective: The aim of this study was to investigate the association between retinal artery occlusion (RAO), subretinal drusenoid deposits (SDD), and choroidal circulation.

Patients and methods: Patients with RAO and healthy age-matched volunteers were included in this study. The presence of SDD, choriocapillaris perfusion area, and subfoveal choroidal thickness were analyzed using optical coherence tomography (OCT) and OCT angiography.

Results: In total, 25 patients with RAO (14 women and 11 men, 71.5 ± 8.9 years) and 19 healthy individuals (10 women and 9 men, 69.0 ± 5.2 years) were included. SDD were found in seven RAO patients (28.0%), among whom four (18.2%) had no age-related macular degeneration. Patients with RAO had a statistically significantly lower choriocapillaris perfusion area and subfoveal choroidal thickness than healthy controls (P < .05).

Conclusion: RAO may have an association with the presence of SDD that agrees with common systemic risk factors and changes of posterior eye segment microcirculation for both conditions.

视网膜动脉闭塞与视网膜下类松膜沉积之间的可能联系:缺失的一环。
背景与目的:本研究的目的是探讨视网膜动脉闭塞(RAO)、视网膜下样膜沉积(SDD)和脉络膜循环之间的关系。患者和方法:本研究纳入了RAO患者和年龄匹配的健康志愿者。通过光学相干断层扫描(OCT)和OCT血管造影分析SDD的存在、绒毛膜毛细血管灌注面积和中央凹下脉络膜厚度。结果:共纳入25例RAO患者(女14例,男11例,71.5±8.9岁)和19例健康人(女10例,男9例,69.0±5.2岁)。在7例(28.0%)RAO患者中发现SDD,其中4例(18.2%)无年龄相关性黄斑变性。RAO患者的绒毛膜毛细血管灌注面积和中央凹下脉络膜厚度均低于健康对照组,差异有统计学意义(P < 0.05)。结论:RAO可能与SDD的存在有关,这与常见的系统性危险因素和两种情况下眼后段微循环的变化一致。
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来源期刊
CiteScore
1.80
自引率
0.00%
发文量
89
期刊介绍: OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.
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