{"title":"Recurrent Neural Network Based on DNA Strand Displacement Circuits and Its Application in Location Prediction.","authors":"Yanfeng Wang, Pengpeng Zhao, Junwei Sun","doi":"10.1109/TNB.2026.3673367","DOIUrl":null,"url":null,"abstract":"<p><p>With the rapid development of science and technology, various intelligent devices continuously generate large amounts of real-time location data. Efficiently utilizing this data for accurate location prediction has become a critical issue in fields such as intelligent transportation and smart logistics. To realize low-power location prediction, this paper constructs a molecular recurrent neural network (RNN) model based on DNA strand displacement (DSD) technology. The RNN model can process sequence data and accurately predict the next position. Firstly, multiple modules are designed based on DSD circuits, including dual-channel weighted summation module, dual-domain data module and Tanh activation function module. Secondly, a RNN model for processing sequence data is constructed using the above modules. Finally, the constructed RNN model successfully achieves position prediction for multiple inputs and a single output. The robustness and accuracy of the neural network are verified through data experiment. It has been demonstrated that DNA molecules can effectively process complex sequence data. This method holds significant potential in the field of path planning. This method holds significant potential in the field of path planning. This paper uses MAE and RMSE to evaluate the experimental data. The results prove that the RNN model constructed in this paper demonstrates strong accuracy and stability.</p>","PeriodicalId":13264,"journal":{"name":"IEEE Transactions on NanoBioscience","volume":"PP ","pages":""},"PeriodicalIF":4.4000,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on NanoBioscience","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1109/TNB.2026.3673367","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
With the rapid development of science and technology, various intelligent devices continuously generate large amounts of real-time location data. Efficiently utilizing this data for accurate location prediction has become a critical issue in fields such as intelligent transportation and smart logistics. To realize low-power location prediction, this paper constructs a molecular recurrent neural network (RNN) model based on DNA strand displacement (DSD) technology. The RNN model can process sequence data and accurately predict the next position. Firstly, multiple modules are designed based on DSD circuits, including dual-channel weighted summation module, dual-domain data module and Tanh activation function module. Secondly, a RNN model for processing sequence data is constructed using the above modules. Finally, the constructed RNN model successfully achieves position prediction for multiple inputs and a single output. The robustness and accuracy of the neural network are verified through data experiment. It has been demonstrated that DNA molecules can effectively process complex sequence data. This method holds significant potential in the field of path planning. This method holds significant potential in the field of path planning. This paper uses MAE and RMSE to evaluate the experimental data. The results prove that the RNN model constructed in this paper demonstrates strong accuracy and stability.
期刊介绍:
The IEEE Transactions on NanoBioscience reports on original, innovative and interdisciplinary work on all aspects of molecular systems, cellular systems, and tissues (including molecular electronics). Topics covered in the journal focus on a broad spectrum of aspects, both on foundations and on applications. Specifically, methods and techniques, experimental aspects, design and implementation, instrumentation and laboratory equipment, clinical aspects, hardware and software data acquisition and analysis and computer based modelling are covered (based on traditional or high performance computing - parallel computers or computer networks).