Association Between Nasal Septal Deviation and Estimated Pulmonary Artery Pressures—Scoping Review

IF 1.9 4区 医学 Q2 OTORHINOLARYNGOLOGY
Clinical Otolaryngology Pub Date : 2026-06-03 Epub Date: 2026-03-12 DOI:10.1111/coa.70098
Samuel A. Collazo, Kimberly A. Ramirez, Nareg H. Roubinian, Paniz Vafaei, Nancy Jiang, Cullen M. Taylor
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引用次数: 0

Abstract

Objective

Nasal septal deviation (NSD) is a common cause of chronic upper airway obstruction (UAO), and surgical correction via nasal septoplasty results in improvements in airflow. Multiple studies have been conducted to assess possible relationships between chronic UAO (including due to NSD) and cardiorespiratory function (such as pulmonary artery pressures). The objective of this scoping review is to identify and examine the current evidence on the potential relationship between nasal septal deviation, estimated mean pulmonary artery pressure (mPAP), and estimated pulmonary artery systolic pressure (ePASP) in patients who undergo nasal septoplasty.

Data Sources

PubMed, EMBASE, Ovid.

Methods

A scoping review was performed in accordance with the PRISMA Extension for Scoping Reviews guidelines.

Results

Two independent reviewers screened 411 articles; 9 before-after studies met eligibility criteria for review inclusion. There was a total of 458 study participants, of which 395 underwent septoplasty and 63 were matched controls. All studies reported a statistically significant decrease between the pre-operative and post-operative estimated mPAP (p < 0.05) and/or ePASP (p < 0.001) in subjects who underwent nasal septoplasty. Two studies included control participants and reported a statistically significant difference between the pre-operative estimated mPAP of patients with NSD and controls (p < 0.001).

Conclusion

This scoping review highlights the current evidence on the potential relationship between NSD, estimated mPAP, and ePASP in patients who undergo nasal septoplasty for NSD. Further studies of higher statistical and methodological quality are required to assess for cause-and-effect relationships and examine the potential link between chronic UAO and cardiorespiratory function.

鼻中隔偏曲与估计肺动脉压之间的关系——镜检回顾。
目的:鼻中隔偏曲(NSD)是慢性上气道阻塞(UAO)的常见原因,通过鼻中隔成形术进行手术矫正可改善气流。已经进行了多项研究来评估慢性UAO(包括由于NSD)与心肺功能(如肺动脉压)之间的可能关系。本综述的目的是确定和检查鼻中隔偏曲、估计平均肺动脉压(mPAP)和估计肺动脉收缩压(ePASP)在鼻中隔成形术患者中的潜在关系的现有证据。数据来源:PubMed, EMBASE, Ovid。方法:根据PRISMA范围审查扩展指南进行范围审查。结果:两名独立审稿人筛选了411篇文章;9个前后对照研究符合纳入评价的资格标准。共有458名研究参与者,其中395人接受了鼻中隔成形术,63人作为对照。所有的研究都报道了术前和术后估计mPAP之间有统计学意义的下降(p结论:本综述强调了目前关于鼻中隔成形术治疗NSD患者的NSD、估计mPAP和ePASP之间潜在关系的证据。需要更高的统计和方法学质量的进一步研究来评估因果关系,并检查慢性UAO与心肺功能之间的潜在联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Otolaryngology
Clinical Otolaryngology 医学-耳鼻喉科学
CiteScore
4.00
自引率
4.80%
发文量
106
审稿时长
>12 weeks
期刊介绍: Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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