Monica L Y E Jacobs, Willem A R Zwaans, Marc R M Scheltinga, Rudi M H Roumen
{"title":"Success rates of a surgical neurectomy for lateral cutaneous nerve entrapment syndrome (LACNES).","authors":"Monica L Y E Jacobs, Willem A R Zwaans, Marc R M Scheltinga, Rudi M H Roumen","doi":"10.1515/sjpain-2025-0030","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Chronic flank pain is occasionally due to entrapped lateral end branches of intercostal nerves (lateral cutaneous nerve entrapment syndrome, LACNES). If local injection therapy fails, a neurectomy may be considered. The literature on LACNES is limited to case reports and a small case series. Aim of the present study is to determine short- and long-term success rates of a neurectomy in a large group of patients with LACNES.</p><p><strong>Methods: </strong>All adult patients who underwent a neurectomy for LACNES between January 2012 and December 2022 in a single centre of expertise were asked to complete a questionnaire regarding their current pain levels. Primary objectives were short-term (6-12 weeks postoperatively) and long-term (>6 months postoperatively) treatment outcome. A successful outcome was defined as a minimal 50 % pain reduction.</p><p><strong>Results: </strong>Data from 54 of 69 operated patients (81 % female, mean age 47 years) were analysed (78 % response rate). Baseline characteristics of responders and non-responders were not different. A 67 % short-term success rate was observed (n=36). Long-term outcome remained successful in 23 patients (43 %, mean follow-up 23 months). Ten patients had minor complications (delayed wound healing n=6, hematoma n=3, deep vein thrombosis n=1; all recovered after conservative treatment).</p><p><strong>Conclusions: </strong>If local injection therapy fails in LACNES, a lateral neurectomy should be discussed. Approximately half of patients report success on the long-term.</p><p><strong>Trial registration: </strong>The Local Medical Ethics Committee of Máxima Medical Centre number N20.125.</p>","PeriodicalId":47407,"journal":{"name":"Scandinavian Journal of Pain","volume":"26 1","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Pain","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/sjpain-2025-0030","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objectives: Chronic flank pain is occasionally due to entrapped lateral end branches of intercostal nerves (lateral cutaneous nerve entrapment syndrome, LACNES). If local injection therapy fails, a neurectomy may be considered. The literature on LACNES is limited to case reports and a small case series. Aim of the present study is to determine short- and long-term success rates of a neurectomy in a large group of patients with LACNES.
Methods: All adult patients who underwent a neurectomy for LACNES between January 2012 and December 2022 in a single centre of expertise were asked to complete a questionnaire regarding their current pain levels. Primary objectives were short-term (6-12 weeks postoperatively) and long-term (>6 months postoperatively) treatment outcome. A successful outcome was defined as a minimal 50 % pain reduction.
Results: Data from 54 of 69 operated patients (81 % female, mean age 47 years) were analysed (78 % response rate). Baseline characteristics of responders and non-responders were not different. A 67 % short-term success rate was observed (n=36). Long-term outcome remained successful in 23 patients (43 %, mean follow-up 23 months). Ten patients had minor complications (delayed wound healing n=6, hematoma n=3, deep vein thrombosis n=1; all recovered after conservative treatment).
Conclusions: If local injection therapy fails in LACNES, a lateral neurectomy should be discussed. Approximately half of patients report success on the long-term.
Trial registration: The Local Medical Ethics Committee of Máxima Medical Centre number N20.125.