Effects of electroacupuncture combined with flurbiprofen axetil on postoperative pain and early functional recovery after breast cancer surgery.

IF 3.6 Q3 ONCOLOGY
Bi-Mei He, Xiao-Lin Sun, Xiao-Yu Huang, Sen-Sen Zhang, Qing-Xiong Hong
{"title":"Effects of electroacupuncture combined with flurbiprofen axetil on postoperative pain and early functional recovery after breast cancer surgery.","authors":"Bi-Mei He, Xiao-Lin Sun, Xiao-Yu Huang, Sen-Sen Zhang, Qing-Xiong Hong","doi":"10.5306/wjco.v17.i2.114431","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Breast cancer surgery often leads to acute postoperative pain that affects early recovery. Electroacupuncture (EA) is a potential adjunct to analgesics such as flurbiprofen axetil (FA), but evidence on its perioperative benefits remains limited.</p><p><strong>Aim: </strong>To investigate the effects of EA combined with FA on postoperative pain and early functional recovery after breast cancer surgery.</p><p><strong>Methods: </strong>A total of 130 patients with breast cancer were randomly divided into EA group (<i>n</i> = 65) and control group (<i>n</i> = 65). Patients received EA or sham acupuncture from 30 minutes before anesthesia induction until surgery end. Both groups received FA postoperatively. We observed the occurrence of postoperative pain (incidence of moderate-to-severe pain during movement and at rest, Visual Analog Scale score) at 24 hours, 48 hours, 72 hours postoperatively, the score of basic activities of daily living (BADL) at 24 hours postoperatively and complications after surgery in both groups of patients.</p><p><strong>Results: </strong>Compared with the control group, the EA group lowered the incidence of moderate-to-severe movement-evoked pain at 24 hours postoperatively (<i>P</i> < 0.05), and reduced Visual Analog Scale scores during movement and at rest 24 hours after surgery (<i>P</i> < 0.01). The scores of BADL for grooming, dressing, toileting, and transferring (moving in and out of a bed or chair) were significantly better in the EA group than in the control group 24 hours after surgery (<i>P</i> < 0.05), the total BADL score was significantly higher (<i>P</i> < 0.01). The incidence of postoperative complications (nausea, vomiting, loss of appetite) was significantly reduced in the EA group (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>EA combined with flurbiprofen FA can reduce the occurrence of postoperative pain and complications, improve early postoperative functional recovery after breast cancer surgery.</p>","PeriodicalId":23802,"journal":{"name":"World journal of clinical oncology","volume":"17 2","pages":"114431"},"PeriodicalIF":3.6000,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12968528/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of clinical oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5306/wjco.v17.i2.114431","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Breast cancer surgery often leads to acute postoperative pain that affects early recovery. Electroacupuncture (EA) is a potential adjunct to analgesics such as flurbiprofen axetil (FA), but evidence on its perioperative benefits remains limited.

Aim: To investigate the effects of EA combined with FA on postoperative pain and early functional recovery after breast cancer surgery.

Methods: A total of 130 patients with breast cancer were randomly divided into EA group (n = 65) and control group (n = 65). Patients received EA or sham acupuncture from 30 minutes before anesthesia induction until surgery end. Both groups received FA postoperatively. We observed the occurrence of postoperative pain (incidence of moderate-to-severe pain during movement and at rest, Visual Analog Scale score) at 24 hours, 48 hours, 72 hours postoperatively, the score of basic activities of daily living (BADL) at 24 hours postoperatively and complications after surgery in both groups of patients.

Results: Compared with the control group, the EA group lowered the incidence of moderate-to-severe movement-evoked pain at 24 hours postoperatively (P < 0.05), and reduced Visual Analog Scale scores during movement and at rest 24 hours after surgery (P < 0.01). The scores of BADL for grooming, dressing, toileting, and transferring (moving in and out of a bed or chair) were significantly better in the EA group than in the control group 24 hours after surgery (P < 0.05), the total BADL score was significantly higher (P < 0.01). The incidence of postoperative complications (nausea, vomiting, loss of appetite) was significantly reduced in the EA group (P < 0.05).

Conclusion: EA combined with flurbiprofen FA can reduce the occurrence of postoperative pain and complications, improve early postoperative functional recovery after breast cancer surgery.

电针联合氟比洛芬酯对乳腺癌术后疼痛及早期功能恢复的影响。
背景:乳腺癌手术常导致急性术后疼痛,影响早期恢复。电针(EA)是氟比洛芬酯(FA)等镇痛药的潜在辅助,但其围手术期益处的证据仍然有限。目的:探讨EA联合FA对乳腺癌术后疼痛及早期功能恢复的影响。方法:将130例乳腺癌患者随机分为EA组(n = 65)和对照组(n = 65)。患者从麻醉诱导前30分钟开始接受EA或假针灸治疗,直至手术结束。两组术后均接受FA治疗。观察两组患者术后24小时、48小时、72小时的疼痛发生率(运动和静止时中重度疼痛发生率、视觉模拟量表评分)、术后24小时的日常生活基本活动(BADL)评分及术后并发症。结果:与对照组相比,EA组术后24小时中重度运动诱发疼痛发生率降低(P < 0.05),术后24小时运动和休息时视觉模拟量表评分降低(P < 0.01)。术后24 h, EA组梳妆、穿衣、如厕、翻身(进出床或椅子)BADL评分均显著优于对照组(P < 0.05),总BADL评分显著高于对照组(P < 0.01)。EA组术后恶心、呕吐、食欲不振等并发症发生率明显降低(P < 0.05)。结论:EA联合氟比洛芬FA可减少乳腺癌术后疼痛及并发症的发生,改善术后早期功能恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
585
期刊介绍: The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书