Ecological Momentary Assessment of Person-Reported Outcomes in Diabetes: Unlocking Insights with Continuous Glucose Monitoring and the Potential for Precision Medicine.

IF 7.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Dominic Ehrmann, Norbert Hermanns, Andreas Schmitt, Laura Y Klinker, Bernhard Kulzer
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Abstract

PURPOSE OF REVIEW: Diabetes self-management is accompanied by time-varying emotional and motivational challenges that impact mental health. These day-to-day fluctuations can be assessed via ecological momentary assessment (EMA), that allows the repeated sampling of psychosocial variables in everyday life. The benefits of EMA over questionnaires mirror the benefits of continuous glucose monitoring (CGM) over HbA1c. We describe the insights generated by combining EMA and CGM and highlight its potential. RECENT FINDINGS: Research shows that glucose levels can influence subsequent mood, stress, cognitive functioning, and symptom reporting, with nocturnal hypoglycemia and overnight glucose being particularly relevant. Studies demonstrated the importance of differentiating between subjective person-interpreted and objectively sensor-assessed glucose levels. N-of-1 analyses revealed relevant intraindividual differences in the association between glycemic and psychosocial parameters. Combining EMA and CGM can enhance our understanding of the dynamic relationship between glycemic and psychosocial variables, supporting precision medicine approaches for mental health in diabetes.

Abstract Image

糖尿病患者报告结果的生态瞬时评估:通过持续血糖监测和精准医学潜力解锁见解。
综述的目的:糖尿病自我管理伴随着影响心理健康的时变情绪和动机挑战。这些日常波动可以通过生态瞬时评估(EMA)进行评估,该评估允许对日常生活中的社会心理变量进行重复抽样。EMA优于问卷调查的好处反映了连续血糖监测(CGM)优于HbA1c的好处。我们描述了结合EMA和CGM产生的见解,并强调了其潜力。最新发现:研究表明,葡萄糖水平可以影响随后的情绪、压力、认知功能和症状报告,夜间低血糖和夜间血糖特别相关。研究表明区分主观的个人解释和客观的传感器评估血糖水平的重要性。N-of-1分析揭示了血糖和社会心理参数之间相关的个体差异。结合EMA和CGM可以增强我们对血糖和社会心理变量之间动态关系的理解,支持糖尿病患者心理健康的精准医学方法。
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来源期刊
CiteScore
9.80
自引率
0.00%
发文量
52
审稿时长
6-12 weeks
期刊介绍: The goal of this journal is to publish cutting-edge reviews on subjects pertinent to all aspects of diabetes epidemiology, pathophysiology, and management. We aim to provide incisive, insightful, and balanced contributions from leading experts in each relevant domain that will be of immediate interest to a wide readership of clinicians, basic scientists, and translational investigators. We accomplish this aim by appointing major authorities to serve as Section Editors in key subject areas across the discipline. Section Editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year on their topics, in a crisp and readable format. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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