The Overlap of Migraine and Transient Global Amnesia: A Case Report and Literature Review on the Concept of "Migramnesia".

IF 0.6 Q4 CLINICAL NEUROLOGY

Case Reports in Neurology Pub Date : 2026-02-09 eCollection Date: 2026-01-01 DOI:10.1159/000550438

Kaveh Bahrami, Jamshid Tabeshpour, Fereydun Moradi

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引用次数: 0

Abstract

Introduction: The pathophysiological relationship between migraine and transient global amnesia (TGA) remains unclear. We present a case of TGA occurring temporally with a migraine attack and review the existing literature on this potential association, sometimes termed "migramnesia."

Case presentation: A 58-year-old man with a history of episodic migraine with aura experienced a severe typical migraine headache. Approximately 3 h after onset, he awoke with profound anterograde and retrograde amnesia lasting 3 h, meeting clinical criteria for TGA. He had no recollection of the amnestic episode or the preceding headache. Brain MRI was unremarkable.

Conclusion: This case adds to the limited number of reports describing a temporal link between migraine and TGA events. A review of the literature reveals conflicting evidence regarding migraine as a risk factor for TGA recurrence. While our case and some studies suggest a plausible association, the evidence is inconsistent. This case highlights the need for further research, including rigorous prospective studies and analyses of potential migraine-related subgroups within TGA populations, to clarify any underlying pathophysiological connections.

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偏头痛与短暂性全局性遗忘的重叠：一例病例报告及关于“偏头痛”概念的文献综述。

偏头痛与短暂性全身性遗忘（TGA）之间的病理生理关系尚不清楚。我们报告一例暂时性TGA伴偏头痛发作的病例，并回顾了现有文献对这种潜在关联的研究，有时被称为“偏头痛遗忘症”。病例介绍：一名58岁男性，有发作性偏头痛先兆病史，经历了严重的典型偏头痛。发病后约3小时，患者醒来时出现深度顺行性和逆行性遗忘，持续3小时，符合TGA的临床标准。他不记得刚才的失忆，也不记得之前的头痛。脑MRI未见异常。结论：本病例增加了有限数量的报道，描述偏头痛和TGA事件之间的时间联系。对文献的回顾揭示了偏头痛作为TGA复发的危险因素的相互矛盾的证据。虽然我们的案例和一些研究表明了一种合理的联系，但证据并不一致。该病例强调了进一步研究的必要性，包括严格的前瞻性研究和TGA人群中潜在偏头痛相关亚群的分析，以阐明任何潜在的病理生理联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Neurology Medicine-Neurology (clinical)

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： This new peer-reviewed online-only journal publishes original case reports covering the entire spectrum of neurology. Clinicians and researchers are given a tool to disseminate their personal experience to a wider public as well as to review interesting cases encountered by colleagues all over the world. To complement the contributions supplementary material is welcomed. The reports are searchable according to the key words supplied by the authors; it will thus be possible to search across the entire growing collection of case reports with universally used terms, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.