Open conversion for endograft infection using the Ovation Alto endograft

Yoshikatsu Nomura, Mikoto Hata, Masashi Nakamura, Sonoko Eizawa, Satoru Eizawa, Hiroshi Tanaka, Hirohisa Murakami
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Abstract

The Ovation Alto device exhibits unique adaptive sealing owing to its polymer-filled sealing ring and has a large bare stent on the proximal side with no stent in the main body portion. We report a case of device infection after endovascular aneurysm repair (EVAR) using the Ovation Alto device. An 85-year-old man with a history EVAR using the Ovation Alto for abdominal aortic aneurysm (AAA) presented two years postoperatively with fever and pyogenic arthritis. Imaging revealed an enlarged AAA, a new type II endoleak, and periaortic inflammation. Laboratory findings showed elevated inflammatory markers, and Streptococcus dysgalactiae was detected in synovial fluid. A diagnosis of endograft infection and septic arthritis was made. Open conversion was performed via laparotomy. Proximal aortic control was achieved at the mid-crown above the renal arteries, and the distal stent graft leg was removed. Extensive debridement was performed, followed by graft replacement and omental wrapping. The fabric portion was explanted, while the bare stent was left in situ. Postoperatively, the patient underwent arthroscopic debridement and local antibiotic therapy for septic arthritis, followed by systemic antibiotics. Although the patient’s infection was controlled, he was ultimately diagnosed with advanced colorectal cancer with liver metastases, leading to death six months after surgery. This case highlights the complexity of managing stent graft infections after EVAR with the Ovation Alto. While complete device explantation may not always be feasible due to anatomical constraints, tailored surgical strategies can achieve infection control.
使用Ovation Alto内移植物治疗内移植物感染的开放性转化
Ovation Alto设备由于其聚合物填充密封环而具有独特的自适应密封,并且在近端有一个大的裸支架,主体部分没有支架。我们报告一例使用Ovation Alto设备进行血管内动脉瘤修复(EVAR)后设备感染的病例。一名85岁男性,使用Ovation Alto进行腹主动脉瘤(AAA)的EVAR病史,术后两年出现发烧和化脓性关节炎。影像学显示AAA增大,新的II型内漏,主动脉周围炎症。实验室结果显示炎症标志物升高,并在滑液中检测到乳酸异常链球菌。诊断为移植物感染和脓毒性关节炎。通过剖腹手术进行开放转换。近端主动脉在肾动脉上方的中冠处得到控制,远端支架移植腿被移除。行广泛清创,随后行移植物置换和网膜包裹。织物部分被移出,而裸露的支架留在原位。术后,患者接受关节镜清创和脓毒性关节炎局部抗生素治疗,随后全身抗生素治疗。尽管患者的感染得到了控制,但他最终被诊断为晚期结直肠癌伴肝转移,在手术后6个月死亡。本病例强调了Ovation Alto处理EVAR后支架感染的复杂性。虽然由于解剖学上的限制,完全的器械外植可能并不总是可行的,但量身定制的手术策略可以实现感染控制。
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