Connor R Volpi, John Chama, Ruxton Adebiyi, Jumoke A Aigoro, Yerima Jibrin Bawa, Kazeem E Kolawole, Uchenna Ononaku, Naomi Ayuba, Ashley Shutt, Abayomi Aka, Stephen E Goldstone, Patrick Dakum, Joel M Palefsky, Sylvia Adebajo, Karin E Tobin, Rebecca G Nowak
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引用次数: 0
Abstract
Background: Sexual minority men (SMM) living with HIV face an elevated risk of anal cancer, and SMM-affirming HIV clinics serve as vital entry points for cancer prevention. We evaluated human papillomavirus (HPV) knowledge, vaccine acceptability and whether time living with HIV was associated with anal cancer symptom awareness.
Methods: A cross-sectional survey was conducted at an HIV clinic offering anal cancer prevention in Abuja, Nigeria. Descriptive statistics were used to summarize HPV knowledge and vaccine acceptability. Multivariable negative binomial regression evaluated the number of anal cancer symptoms correctly reported using adjusted prevalence ratios (aPR) and 95% confidence intervals (CIs).
Results: Among 249 SMM living with HIV, 20.5% reported having heard of HPV. Fewer than 20% correctly identified key anal cancer symptoms, including anal bleeding (15.7%) and a lump or mass in the anus (16.9%). Time living with HIV was initially associated with anal cancer symptom awareness, but not after adjustment (aPR 1.02, 95% CI 0.98-1.07). Other independent predictors of anal cancer symptom awareness were anal cancer screening (aPR 1.51, 95% CI 1.15-1.97) and knowing HPV vaccine can prevent anal cancer (aPR 1.52, 95% CI 1.18-1.98). Despite low HPV awareness, 93.6% of participants reported willingness to receive HPV vaccine.
Conclusion: Integrating cancer prevention services into SMM-affirming HIV care may offer an opportunity to strengthen HPV-related knowledge and reduce cancer disparities.
背景：感染艾滋病毒的性少数男性（SMM）患肛门癌的风险较高，而确认SMM的艾滋病毒诊所是预防癌症的重要切入点。我们评估了人乳头瘤病毒（HPV）知识、疫苗可接受性以及感染HIV的时间是否与肛门癌症状意识相关。方法：在尼日利亚阿布贾的一家提供肛门癌预防的艾滋病毒诊所进行了横断面调查。描述性统计用于总结HPV知识和疫苗可接受性。使用校正患病率（aPR）和95%置信区间（CIs），多变量负二项回归评估正确报告的肛门癌症状的数量。结果：在249名HIV感染者中，20.5%的人报告听说过HPV。不到20%的人正确识别出肛门癌的主要症状，包括肛门出血（15.7%）和肛门肿块或肿块（16.9%）。感染艾滋病毒的时间最初与肛门癌症状意识相关，但调整后不相关（aPR 1.02, 95% CI 0.98-1.07）。肛门癌症状意识的其他独立预测因子为肛门癌筛查（aPR 1.51, 95% CI 1.15-1.97）和知道HPV疫苗可以预防肛门癌（aPR 1.52, 95% CI 1.18-1.98）。尽管HPV意识较低，但93.6%的参与者表示愿意接种HPV疫苗。结论：将癌症预防服务整合到smm确认HIV护理中可能为加强hpv相关知识和减少癌症差异提供机会。
期刊介绍：
Sexual Health publishes original and significant contributions to the fields of sexual health including HIV/AIDS, Sexually transmissible infections, issues of sexuality and relevant areas of reproductive health. This journal is directed towards those working in sexual health as clinicians, public health practitioners, researchers in behavioural, clinical, laboratory, public health or social, sciences. The journal publishes peer reviewed original research, editorials, review articles, topical debates, case reports and critical correspondence.
Officially sponsored by:
The Australasian Chapter of Sexual Health Medicine of RACP
Sexual Health Society of Queensland
Sexual Health is the official journal of the International Union against Sexually Transmitted Infections (IUSTI), Asia-Pacific, and the Asia-Oceania Federation of Sexology.
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