Non-canonical muscle stem cells and other lessons from regenerative vertebrates.

IF 7 1区医学 Q1 CELL & TISSUE ENGINEERING

npj Regenerative Medicine Pub Date : 2026-03-10 DOI:10.1038/s41536-026-00468-9

Vijayishwer Singh Jamwal, Wouter Masselink, Karen Crawford, Prayag Murawala

引用次数: 0

Abstract

In this perspective, we explore the developmental mechanisms of muscle stem cells in multiple non-mammalian vertebrate species, and we compare these phenomena to those in mammals. Particularly, we discuss two recently described populations of noncanonical muscle progenitors in regenerative vertebrates: one in zebrafish and one in axolotl. We discuss the capabilities of these two populations during muscle development and regeneration, including the implications for muscle repair in mammals.

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非典型肌肉干细胞和其他再生脊椎动物的经验教训。

从这个角度来看，我们探索了多种非哺乳动物脊椎动物肌肉干细胞的发育机制，并将这些现象与哺乳动物进行了比较。特别地，我们讨论了最近在再生脊椎动物中描述的两个非规范肌肉祖细胞群体：一个在斑马鱼中，一个在蝾螈中。我们讨论了这两个种群在肌肉发育和再生过程中的能力，包括对哺乳动物肌肉修复的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

npj Regenerative Medicine Engineering-Biomedical Engineering

CiteScore

10.00

自引率

1.40%

发文量

审稿时长

12 weeks

期刊介绍： Regenerative Medicine, an innovative online-only journal, aims to advance research in the field of repairing and regenerating damaged tissues and organs within the human body. As a part of the prestigious Nature Partner Journals series and in partnership with ARMI, this high-quality, open access journal serves as a platform for scientists to explore effective therapies that harness the body's natural regenerative capabilities. With a focus on understanding the fundamental mechanisms of tissue damage and regeneration, npj Regenerative Medicine actively encourages studies that bridge the gap between basic research and clinical tissue repair strategies.