Injecting OVD temporarily seal the edge of the retinectomy to prevent subretinal perfluorocarbon liquid droplets retention and retinal slippage during fluid-air exchange.

IF 3.8 Q2 OPHTHALMOLOGY
Zifang He, Yinong Guo, Yilinuer Yilihaer, Suyu Liu, Yifei Tang, Lv Xie, Ye Zhang, Yajun Liu, Zhenggao Xie
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引用次数: 0

Abstract

BACKGROUND: To investigate effect of the injection of ophthalmic viscosurgical device (DisCoVisc) temporarily seal the edge of the retinectomy to prevent subretinal perfluorocarbon liquid (PFCL) droplets retention and retinal slippage during fluid-air exchange. METHODS: PFCL was injected, with the fluid level extended 3–5 mm above the posterior edge of the retinectomy. Laser photocoagulation was applied around the edge of the retinectomy. DisCoVisc was then injected under PFCL and evenly applied along the edge of the retinectomy to achieve temporary and complete sealing. Under infusion fluid, PFCL was completely removed. Then fluid-air exchange was applied. Finally, silicone oil was injected for intravitreal tamponade. RESULTS: A total of 9 patients (9 eyes) were included in this study, all of whom underwent retinectomy. On postoperative day 1, the retinas of all patients remained fully attached without any flap inversion or slippage. No subretinal PFCL droplets were detected. At last visit, the mean IOP was 15.61 ± 7.18 mmHg, without significant difference compared to preoperative IOP (13.39 ± 4.97 mmHg) (P = 0.455), but the mean post-operative BCVA (1.01 ± 0.62) logMAR (Snellen equivalent 20/200) with a significant difference compared to preoperative BCVA (2.04 ± 1.42) logMAR (Snellen equivalent 20/2190) (P = 0.031). CONCLUSIONS: Injecting DisCoVisc under PFCL to temporarily seal the edge of the retinectomy effectively prevents infusion fluid and PFCL droplets from entering the subretinal space during fluid–air exchange, thereby reducing the risk of retinal slippage and subretinal PFCL retention. CLINICAL TRIAL NUMBER: Not applicable.

注射OVD暂时封闭视网膜切除术边缘,以防止在液气交换过程中视网膜下全氟碳液滴潴留和视网膜滑动。
背景:探讨注射眼粘手术装置(DisCoVisc)暂时封闭视网膜切除术边缘以防止液气交换过程中视网膜下全氟碳液体(PFCL)液滴潴留和视网膜滑脱的效果。方法:注射PFCL,液面延伸至视网膜切除术后缘以上3 ~ 5mm。在视网膜切除术边缘周围应用激光光凝。然后在PFCL下注射DisCoVisc,沿视网膜切除术边缘均匀涂抹,以实现暂时和完全的封闭。在输液下,PFCL被完全清除。然后采用气液交换。最后注射硅油进行玻璃体内填塞。结果:本研究共纳入9例患者(9只眼),均行视网膜切除术。术后第1天,所有患者的视网膜均保持完全附着,无任何皮瓣翻转或滑脱。视网膜下未见PFCL滴。末次访视时平均IOP为15.61±7.18 mmHg,与术前IOP(13.39±4.97 mmHg)无显著差异(P = 0.455),但术后平均BCVA(1.01±0.62)logMAR (Snellen当量20/200)与术前BCVA(2.04±1.42)logMAR (Snellen当量20/2190)有显著差异(P = 0.031)。结论:在PFCL下注射DisCoVisc暂时封闭视网膜切除术边缘,可有效防止输液液和PFCL液滴在液气交换过程中进入视网膜下间隙,从而降低视网膜滑脱和视网膜下PFCL潴留的风险。临床试验编号:不适用。
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来源期刊
CiteScore
3.50
自引率
4.30%
发文量
81
审稿时长
19 weeks
期刊介绍: International Journal of Retina and Vitreous focuses on the ophthalmic subspecialty of vitreoretinal disorders. The journal presents original articles on new approaches to diagnosis, outcomes of clinical trials, innovations in pharmacological therapy and surgical techniques, as well as basic science advances that impact clinical practice. Topical areas include, but are not limited to: -Imaging of the retina, choroid and vitreous -Innovations in optical coherence tomography (OCT) -Small-gauge vitrectomy, retinal detachment, chromovitrectomy -Electroretinography (ERG), microperimetry, other functional tests -Intraocular tumors -Retinal pharmacotherapy & drug delivery -Diabetic retinopathy & other vascular diseases -Age-related macular degeneration (AMD) & other macular entities
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