{"title":"Fight, Flight, Fawn, Freeze: Rethinking Substance Use Through a Stress Response Lens.","authors":"Angel B Algarin, Ji-Young Lee, Xiangming Zhan","doi":"10.1007/s40429-026-00723-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>This paper proposes a stress-response framework for understanding substance use in the context of adversity, integrating fight (resistance), flight (adaptive coping), freeze (maladaptive coping), and fawn (strategic assimilation/appeasement) responses, with resilience as a moderating factor.</p><p><strong>Recent findings: </strong>Evidence indicates that adaptive resistance and coping can protect against substance use, while maladaptive resistance, maladaptive coping, and fawning may increase long-term risk despite short-term relief. Resilience, both individual and collective, can buffer adversity's effects and enhance positive stress responses, though measurement and conceptual inconsistencies limit cross-study synthesis.</p><p><strong>Summary: </strong>Advancing research on adversity and substance use requires the use of validated measures, the simultaneous assessment of multiple stress responses to capture their interactions, and greater theorization of resistance and fawning/strategic assimilation, which remain underdeveloped and understudied in substance use research.</p>","PeriodicalId":52300,"journal":{"name":"Current Addiction Reports","volume":"13 1","pages":"21"},"PeriodicalIF":4.6000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960391/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Addiction Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s40429-026-00723-5","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/4 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"SUBSTANCE ABUSE","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: This paper proposes a stress-response framework for understanding substance use in the context of adversity, integrating fight (resistance), flight (adaptive coping), freeze (maladaptive coping), and fawn (strategic assimilation/appeasement) responses, with resilience as a moderating factor.
Recent findings: Evidence indicates that adaptive resistance and coping can protect against substance use, while maladaptive resistance, maladaptive coping, and fawning may increase long-term risk despite short-term relief. Resilience, both individual and collective, can buffer adversity's effects and enhance positive stress responses, though measurement and conceptual inconsistencies limit cross-study synthesis.
Summary: Advancing research on adversity and substance use requires the use of validated measures, the simultaneous assessment of multiple stress responses to capture their interactions, and greater theorization of resistance and fawning/strategic assimilation, which remain underdeveloped and understudied in substance use research.
期刊介绍:
This journal focuses on the prevention, assessment and diagnosis, and treatment of addiction. Designed for physicians and other mental health professionals who need to keep up-to-date with the latest research, Current Addiction Reports offers expert reviews on the most recent and important research in addiction. We accomplish this by appointing leaders in the field to serve as Section Editors in key subject areas and disciplines, such asAlcoholTobaccoStimulants, cannabis, and club drugsBehavioral addictionsGender disparities in addictionComorbid psychiatric disorders and addictionSubstance abuse disorders and HIVSection Editors, in turn, select the most pressing topics as well as experts to evaluate the latest research, report on any controversial discoveries or hypotheses of interest, and ultimately bring readers up-to-date on the topic. Articles represent interdisciplinary endeavors with research from fields such as psychiatry, psychology, pharmacology, epidemiology, and neuroscience.Additionally, an international Editorial Board—representing a range of disciplines within addiction medicine—ensures that the journal content includes current, emerging research and suggests articles of special interest to their country or region.