Matthew K. Wun, Michael H. Court, Nicolas F. Villarino, Richard Malik
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引用次数: 0
Abstract
Injectable meloxicam remains widely used in feline practice despite its association with acute kidney injury (AKI). Evidence of this association was apparent in the results of a clinical trial submitted to the U.S. Food and Drug Administration as part of a New Animal Drug Application (NADA) Freedom of Information Summary. These data, however, were omitted from the published version of that clinical trial in the Journal of the American Veterinary Medical Association (JAVMA). The study's financial sponsorship by the drug manufacturer raises ethical concerns, especially given meloxicam's ongoing and enthusiastic promotion by veterinary organizations also financially supported by the manufacturer. This viewpoint questions meloxicam's approval process and highlights the potential influence of pharmaceutical industry sponsorship on veterinary prescribing practices and policy.
期刊介绍：
The Journal of Veterinary Pharmacology and Therapeutics (JVPT) is an international journal devoted to the publication of scientific papers in the basic and clinical aspects of veterinary pharmacology and toxicology, whether the study is in vitro, in vivo, ex vivo or in silico. The Journal is a forum for recent scientific information and developments in the discipline of veterinary pharmacology, including toxicology and therapeutics. Studies that are entirely in vitro will not be considered within the scope of JVPT unless the study has direct relevance to the use of the drug (including toxicants and feed additives) in veterinary species, or that it can be clearly demonstrated that a similar outcome would be expected in vivo. These studies should consider approved or widely used veterinary drugs and/or drugs with broad applicability to veterinary species.
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