Felix Inchausti, Nancy V García-Poveda, Alejandro Ballesteros-Prados, Eduardo Fonseca-Pedrero, Angus MacBeth, Raffaele Popolo, Giancarlo Dimaggio
{"title":"Metacognitive Interpersonal Group Therapy for Adolescents With Personality Disorders: Results From the METAMIND-A Pilot Randomized Controlled Trial.","authors":"Felix Inchausti, Nancy V García-Poveda, Alejandro Ballesteros-Prados, Eduardo Fonseca-Pedrero, Angus MacBeth, Raffaele Popolo, Giancarlo Dimaggio","doi":"10.1097/NMD.0000000000001869","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This pilot RCT evaluated the feasibility, acceptability, and preliminary effects of Metacognitive Interpersonal Group Therapy for Adolescents (MIT-GA) compared with waiting list plus treatment-as-usual (WL+TAU).</p><p><strong>Methods: </strong>One hundred adolescents (14-18 years) meeting DSM-IV criteria for PDs (excluding antisocial PD) were randomized to MIT-GA or WL+TAU for 4 months. Primary outcomes included treatment acceptability, psychosocial functioning (CGAS, IIP-64), and symptom severity (SCL-90-R GSI). Secondary outcomes were depression (Y-BDI), caregiver stress (PSS), and parental self-efficacy (BPSES). Mechanisms of change included metacognition (MAS-A), alexithymia (TAS-20), and impulsivity (BIS-11).</p><p><strong>Results: </strong>MIT-GA participants showed greater improvements in psychosocial functioning (d = 0.80) and parental stress (d = 0.65) versus WL+TAU. No significant between-group differences were found in overall symptom severity. MIT-GA also improved metacognition, alexithymia, and attentional impulsivity. No adverse events were reported.</p><p><strong>Conclusions: </strong>These findings support the feasibility and potential utility of MIT-GA for adolescents with PDs.</p>","PeriodicalId":16480,"journal":{"name":"Journal of Nervous and Mental Disease","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nervous and Mental Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/NMD.0000000000001869","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: This pilot RCT evaluated the feasibility, acceptability, and preliminary effects of Metacognitive Interpersonal Group Therapy for Adolescents (MIT-GA) compared with waiting list plus treatment-as-usual (WL+TAU).
Methods: One hundred adolescents (14-18 years) meeting DSM-IV criteria for PDs (excluding antisocial PD) were randomized to MIT-GA or WL+TAU for 4 months. Primary outcomes included treatment acceptability, psychosocial functioning (CGAS, IIP-64), and symptom severity (SCL-90-R GSI). Secondary outcomes were depression (Y-BDI), caregiver stress (PSS), and parental self-efficacy (BPSES). Mechanisms of change included metacognition (MAS-A), alexithymia (TAS-20), and impulsivity (BIS-11).
Results: MIT-GA participants showed greater improvements in psychosocial functioning (d = 0.80) and parental stress (d = 0.65) versus WL+TAU. No significant between-group differences were found in overall symptom severity. MIT-GA also improved metacognition, alexithymia, and attentional impulsivity. No adverse events were reported.
Conclusions: These findings support the feasibility and potential utility of MIT-GA for adolescents with PDs.
期刊介绍:
The Journal of Nervous and Mental Disease publishes peer-reviewed articles containing new data or ways of reorganizing established knowledge relevant to understanding and modifying human behavior, especially that defined as impaired or diseased, and the context, applications and effects of that knowledge. Our policy is summarized by the slogan, "Behavioral science for clinical practice." We consider articles that include at least one behavioral variable, clear definition of study populations, and replicable research designs. Authors should use the active voice and first person whenever possible.