Activity determination of 68Ga by an extended TDCR-Čerenkov method

IF 1.8 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Applied Radiation and Isotopes Pub Date : 2026-06-01 Epub Date: 2026-03-04 DOI:10.1016/j.apradiso.2026.112544

Zihao Fan , Zhijie Yang , Haoran Liu , Juncheng Liang , Changhao Sun , Yifan Tian

引用次数: 0

Abstract

⁶⁸Ga is a crucial radionuclide for positron emission tomography (PET). It decays by β⁺ transition and electron capture to the ground state and several excited levels of ⁶⁸Zn. The energy of emitted positrons is high enough to enable activity measurement via Čerenkov radiation detection in aqueous solution. Furthermore, the Čerenkov threshold effect inherently excludes the contribution of electron-capture transitions in ⁶⁸Ga during the measurement. In this work, the current TDCR-Čerenkov analytical model was extended for the efficiency computation based on the decay scheme of ⁶⁸Ga. Then the results derived from TDCR-Čerenkov method were compared to those from the well-established 4πβ(Č)-γ method. A discrepancy of 0.21% was found, indicating good agreement within the uncertainty range.

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扩展TDCR-Čerenkov法测定68Ga活性。

68Ga是正电子发射断层扫描（PET）的重要放射性核素。它通过β+跃迁和电子捕获衰变到68Zn的基态和几个激发态。发射的正电子的能量足够高，可以通过Čerenkov在水溶液中的辐射检测来测量活度。此外，Čerenkov阈值效应固有地排除了测量期间68Ga中电子捕获跃迁的贡献。本文将现有的TDCR-Čerenkov分析模型扩展为基于68Ga衰减格式的效率计算。并将TDCR-Čerenkov法与4πβ（Č）-γ法进行了比较。误差为0.21%，在不确定度范围内吻合良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.