Organ-ovary crosstalk as a vital determinant of women's health.

Abstract

The ovary is more than just a reproductive organ. Recent evidence in mammalian and invertebrate models consistently highlights novel mechanistic insights into organ-ovary crosstalk via classical hormones and emerging secretomes, such as extracellular vesicles. Thus, the ovary functions as an integral organ to maintain organismal health through crosstalk with various organs.