Clinical, radiographic and histopathological analysis of bone-forming tumors of the oral and maxillofacial region: A 53-year retrospective study.

IF 2.2 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Medicina Oral Patologia Oral Y Cirugia Bucal Pub Date : 2026-03-07 DOI:10.4317/medoral.27793

M-C-M Carvalho, D-F Colares, H-G Morais, A-K Gonzaga, A-D Costa, P-P Santos, L-B Souza

{"title":"Clinical, radiographic and histopathological analysis of bone-forming tumors of the oral and maxillofacial region: A 53-year retrospective study.","authors":"M-C-M Carvalho, D-F Colares, H-G Morais, A-K Gonzaga, A-D Costa, P-P Santos, L-B Souza","doi":"10.4317/medoral.27793","DOIUrl":null,"url":null,"abstract":"Background: Non-odontogenic bone tumors of the jawbones constitute a heterogeneous group of tumors that may arise in various regions of the maxillofacial complex and present as chondroid or bone-forming tumors (BFTs). Therefore, this 53-year retrospective study aimed to evaluate the clinical, radiographic, and histopathological characteristics of BFTs (osteoma-OT, osteoblastoma-OB and osteosarcoma-OS) diagnosed at a single oral pathology referral center in Brazil.Material and methods: Gender, age, symptoms, clinical diagnosis, lesion duration, anatomical site, size of the lesion, and radiographic characteristics were collected from all cases previously diagnosed as BFTs, and all histological sections were reviewed.Results: Among 19.596 cases diagnosed at the service during the study period, 74 (0.37%) were identified as OTs, OBs or OSs, with OTs being the most common (55.4%). There was a predominance of female patients (70.2%), and the mandible was the most affected gnathic bone (84.7%). Radiographically, OTs typically presented as well-delimited, radiopaque lesions (68.4%), whereas OBs (68.4%) and OSs (75.0%) frequently exhibited mixed radiolucent patterns. Histopathologically, OTs were predominantly classified as compact, and OBs were commonly typical. Osteosarcomas were frequently of osteoblastic subtype.Conclusions: Awareness of clinical, radiographic and histopathological characteristics is essential for improving recognition of the distinct profiles of BFTs.","PeriodicalId":49016,"journal":{"name":"Medicina Oral Patologia Oral Y Cirugia Bucal","volume":" ","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2026-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312332/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina Oral Patologia Oral Y Cirugia Bucal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4317/medoral.27793","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Non-odontogenic bone tumors of the jawbones constitute a heterogeneous group of tumors that may arise in various regions of the maxillofacial complex and present as chondroid or bone-forming tumors (BFTs). Therefore, this 53-year retrospective study aimed to evaluate the clinical, radiographic, and histopathological characteristics of BFTs (osteoma-OT, osteoblastoma-OB and osteosarcoma-OS) diagnosed at a single oral pathology referral center in Brazil.

Material and methods: Gender, age, symptoms, clinical diagnosis, lesion duration, anatomical site, size of the lesion, and radiographic characteristics were collected from all cases previously diagnosed as BFTs, and all histological sections were reviewed.

Results: Among 19.596 cases diagnosed at the service during the study period, 74 (0.37%) were identified as OTs, OBs or OSs, with OTs being the most common (55.4%). There was a predominance of female patients (70.2%), and the mandible was the most affected gnathic bone (84.7%). Radiographically, OTs typically presented as well-delimited, radiopaque lesions (68.4%), whereas OBs (68.4%) and OSs (75.0%) frequently exhibited mixed radiolucent patterns. Histopathologically, OTs were predominantly classified as compact, and OBs were commonly typical. Osteosarcomas were frequently of osteoblastic subtype.

Conclusions: Awareness of clinical, radiographic and histopathological characteristics is essential for improving recognition of the distinct profiles of BFTs.

查看原文本刊更多论文

口腔颌面部骨形成肿瘤的临床、影像学及组织病理学分析：一项53年回顾性研究。

背景：颌骨的非牙源性骨肿瘤构成了一组异质性肿瘤，可出现在颌面部复合体的不同区域，并以软骨样或骨形成肿瘤（BFTs）的形式出现。因此，这项为期53年的回顾性研究旨在评估巴西单一口腔病理转诊中心诊断的BFTs（骨瘤- ot、成骨细胞瘤- ob和骨肉瘤- os）的临床、影像学和组织病理学特征。材料和方法：收集既往诊断为BFTs的所有病例的性别、年龄、症状、临床诊断、病变持续时间、解剖部位、病变大小、影像学特征，并复习所有组织学切片。结果：本研究期间就诊的19.596例患者中，有74例（0.37%）被诊断为外伤性、外伤性或外伤性疾病，其中外伤性疾病最多（55.4%）。女性患者居多（70.2%），以下颌骨为主（84.7%）。放射学上，OTs通常表现为界限清晰、不透明的病变（68.4%），而OBs（68.4%）和OSs（75.0%）经常表现为混合的放射透光模式。组织病理学上，OTs主要被分类为致密型，OBs通常是典型的。骨肉瘤多为成骨细胞亚型。结论：了解临床、影像学和组织病理学特征对于提高对BFTs不同特征的认识至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Medicina Oral Patologia Oral Y Cirugia Bucal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： 1. Oral Medicine and Pathology: Clinicopathological as well as medical or surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, as well as orofacial neurological disorders, and systemic conditions with an impact on the oral cavity. 2. Oral Surgery: Surgical management aspects of diseases affecting oral mucosa, salivary glands, maxillary bones, teeth, implants, oral surgical procedures. Surgical management of diseases affecting head and neck areas. 3. Medically compromised patients in Dentistry: Articles discussing medical problems in Odontology will also be included, with a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients. 4. Implantology 5. Periodontology