Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery.

IF 16.6 1区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Trends in biotechnology Pub Date : 2026-10-01 Epub Date: 2026-03-05 DOI:10.1016/j.tibtech.2026.01.008
Ji-Yong Sung, Seung-Min Park, Jae-Ho Cheong
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引用次数: 0

Abstract

Quantum computing has emerged as a potential catalyst for addressing computational bottlenecks that increasingly constrain biotechnologies, including drug discovery, structural biology, and precision medicine. As biological datasets grow in scale and complexity, classical high-performance computing struggles to efficiently model molecular interactions and high-dimensional biological systems. Recent advances in hybrid quantum-classical algorithms and quantum-enhanced machine learning have enabled early proof-of-concept applications on noisy intermediate-scale quantum (NISQ) devices, offering new strategies for molecular simulation, pattern recognition, and optimization. In this opinion article, we critically assess where quantum computing may deliver realistic near-term value for biomedicine, emphasize hybrid workflows as the most viable path forward, and outline how quantum technologies could complement, not replace, existing computational paradigms as the field progresses toward fault-tolerant systems.

生物技术创新的量子计算:生物医学和药物发现的变革潜力。
量子计算已经成为解决日益制约生物技术(包括药物发现、结构生物学和精准医学)的计算瓶颈的潜在催化剂。随着生物数据集规模和复杂性的增长,传统的高性能计算难以有效地模拟分子相互作用和高维生物系统。混合量子经典算法和量子增强机器学习的最新进展使早期概念验证应用能够在噪声中尺度量子(NISQ)设备上实现,为分子模拟、模式识别和优化提供了新的策略。在这篇观点文章中,我们批判性地评估了量子计算在哪些方面可能为生物医学提供现实的近期价值,强调混合工作流程是最可行的前进道路,并概述了随着该领域向容错系统发展,量子技术如何补充而不是取代现有的计算范式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Trends in biotechnology
Trends in biotechnology 工程技术-生物工程与应用微生物
CiteScore
28.60
自引率
1.20%
发文量
198
审稿时长
1 months
期刊介绍: Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).
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