Cardiac lesions in sheep and goats with spontaneous Clostridium perfringens type D enterotoxemia.

IF 2.3 2区农林科学 Q2 PATHOLOGY

Veterinary Pathology Pub Date : 2026-09-01 Epub Date: 2026-03-07 DOI:10.1177/03009858261426544

Emma H Torii, Omar A Gonzales-Viera, Jennine Ochoa, Todd Cornish, Nicolas Streitenberger, Roberto W I Olivares, Hannah Neer, Francisco A Uzal, Asli Mete

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Abstract

A 12-year retrospective search identified 106 sheep and goats diagnosed with Clostridium perfringens type D enterotoxemia, and in which the heart was histologically examined. Twenty cases (20/106, 19%), including 10 sheep and 10 goats, had cardiac lesions that were presumed to be associated with enterotoxemia. The lesions included myocardial degeneration and/or necrosis (n = 16, 80%), hemorrhage (n = 17, 85%), and proteinaceous interstitial edema (n = 6, 30%). Myocardial degeneration and/or necrosis was more frequent in goats (10/10, 100%) compared with sheep (6/10, 60%). Hemorrhage was more frequent in sheep (10/10, 100%) compared with goats (7/10, 70%). Myocardial proteinaceous interstitial edema was exclusive to sheep. Cardiac lesions occur in spontaneous cases of C. perfringens type D enterotoxemia in small ruminants and may play a role in the clinical signs and/or the demise of the animal.

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自发性产气荚膜梭菌D型肠毒血症绵羊和山羊的心脏病变。

一项为期12年的回顾性研究发现，106只绵羊和山羊被诊断为产气荚膜梭菌D型肠毒血症，并对其心脏进行了组织学检查。20例（20/106,19%），包括10只绵羊和10只山羊，有心脏病变，推测与肠毒血症有关。病变包括心肌变性和/或坏死（n = 16, 80%）、出血（n = 17, 85%）和蛋白质间质水肿（n = 6, 30%）。心肌变性和/或坏死在山羊（10/ 10,100%）比绵羊（6/ 10,60%）更常见。绵羊（10/ 10,100 %）比山羊（7/ 10,70 %）出血更频繁。心肌蛋白间质性水肿是绵羊所特有的。小反刍动物自发性产气荚膜荚膜杆菌D型肠毒血症病例中可发生心脏病变，并可能在动物的临床症状和/或死亡中发挥作用。

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来源期刊

Veterinary Pathology 农林科学-病理学

CiteScore

4.70

自引率

8.30%

发文量

审稿时长

2 months

期刊介绍： Veterinary Pathology (VET) is the premier international publication of basic and applied research involving domestic, laboratory, wildlife, marine and zoo animals, and poultry. Bridging the divide between natural and experimental diseases, the journal details the diagnostic investigations of diseases of animals; reports experimental studies on mechanisms of specific processes; provides unique insights into animal models of human disease; and presents studies on environmental and pharmaceutical hazards.