Peri-Implant Reconstruction With Autogenous Bone and Electrolytic Therapy: A Randomized Controlled Clinical Trial

IF 4 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research Pub Date : 2026-03-06 DOI:10.1111/cid.70123

Algirdas Puisys, Samuel Akhondi, Egle Vindasiute-Narbute, Tadas Zvirblis, German O. Gallucci, Ignacio Pedrinaci

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引用次数: 0

Abstract

Objectives

To evaluate the efficacy of peri-implant reconstructive therapy using autogenous tuberosity bone grafts, with or without adjunctive electrolytic therapy, as part of surgical treatment for peri-implantitis.

Methods

This randomized controlled clinical trial included 31 patients diagnosed with peri-implantitis. Participants were assigned to either a control group receiving mechanical debridement and bone grafting or a test group undergoing additional electrolytic cleaning (EC). Clinical parameters assessed included probing pocket depth (PPD) at mesial, buccal, distal, and lingual sites, gingival index (GI), and bleeding on probing (BOP), with measurements taken at baseline and at 12 months post-treatment. Radiographic assessments were conducted at baseline and at the 1-year follow-up to evaluate bone defect fill at mesial and distal sites. Intraoperative bone fill was also assessed at mesial, buccal, distal, and lingual sites on the day of surgery and 6 months post-surgery.

Results

Both groups exhibited statistically significant PPD reductions at all sites and improvements in GI and BOP compared to baseline. No statistically significant differences between groups were found for these clinical parameters. Radiographically, the test group demonstrated significantly greater mean bone defect fill at the mesial site compared to the control group, with gains of 4.6 mm (±1.10 mm) versus 2.5 mm (±1.77 mm), respectively (p = 0.002). Intraoperatively, the distal site showed a mean gain of 4.7 mm (±1.41 mm) in the test group and 3.8 mm (±1.72 mm) in the control group after 6 months; however, this difference was not statistically significant (p = 0.069). Suppuration resolved completely in both groups after 1 year (p < 0.001), with no significant differences between groups.

Conclusions

Peri-implant reconstructive therapy using autogenous bone grafts led to statistically significant clinical and radiographic improvements in both groups. The addition of electrolytic cleaning did not result in significant differences. The absence of histological data, which could not be obtained in this human trial, remains a limitation for confirming re-osseointegration.

查看原文本刊更多论文

自体骨和电解治疗的种植体周围重建：一项随机对照临床试验。

目的：评价自体结节骨移植作为种植体周围炎手术治疗的一部分，配合或不配合电解治疗的疗效。方法：本随机对照临床试验纳入31例诊断为种植体周围炎的患者。参与者被分配到接受机械清创和植骨的对照组或接受额外电解清洁（EC）的试验组。评估的临床参数包括中、颊、远端和舌部的探诊袋深度（PPD）、牙龈指数（GI）和探诊出血（BOP），并在基线和治疗后12个月进行测量。在基线和1年随访时进行影像学评估，以评估中、远端骨缺损填充情况。术中还在手术当天和术后6个月对中、颊、远端和舌部位的骨填充进行了评估。结果：与基线相比，两组在所有部位的PPD均有统计学意义的降低，GI和BOP均有改善。这些临床参数组间无统计学差异。x线摄影显示，与对照组相比，试验组在中端表现出更大的平均骨缺损填充，分别增加4.6 mm（±1.10 mm）和2.5 mm（±1.77 mm）（p = 0.002）。术中6个月后，实验组远端平均增厚4.7 mm（±1.41 mm），对照组平均增厚3.8 mm（±1.72 mm）；但差异无统计学意义（p = 0.069）。结论：采用自体骨移植进行种植体周围重建治疗，两组患者的临床和影像学改善均有统计学意义。电解清洗的加入并没有导致显著的差异。组织学数据的缺失，在这项人体试验中无法获得，仍然是确认再骨整合的限制。

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来源期刊

Clinical Implant Dentistry and Related Research 医学-牙科与口腔外科

CiteScore

6.00

自引率

13.90%

发文量

103

审稿时长

4-8 weeks

期刊介绍： The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.