On the problem of minimizing the epidemic final size for SIR model by social distancing.

IF 2.6 4区 工程技术 Q1 Mathematics
Pierre-Alexandre Bliman, Anas Bouali, Patrice Loisel, Alain Rapaport, Arnaud Virelizier
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引用次数: 0

Abstract

We revisit the problem of minimizing the epidemic final size in the SIR model through social distancing of a bounded intensity. In the existing literature, this problem was considered imposing a priori interval structure on the time period when interventions are enforced. We show that the support of the optimal control is still a single time interval when considering the more general class of controls with an $ L^1 $ constraint on the confinement effort that reduces the infection rate. There is thus no benefit in splitting interventions on several disjoint time periods. However, if the infection rate is known beforehand to change with time once from one value to another one, then we show that the optimal solution may consist in splitting the interventions in at most two disjoint time periods.

基于社会距离最小化SIR模型的疫情最终规模问题
我们重新审视SIR模型中通过有界强度的社会距离最小化流行病最终规模的问题。在现有的文献中,这个问题被认为是强加了一个先验的区间结构的时间段,当干预措施被强制执行。我们表明,当考虑更一般的控制类时,最优控制的支持仍然是一个单一的时间区间,这些控制类对降低感染率的限制努力具有$ L^1 $约束。因此,将干预措施分散在几个互不相关的时间段是没有好处的。然而,如果事先知道感染率随时间变化一次,从一个值到另一个值,那么我们表明,最优解决方案可能包括将干预措施分为最多两个不相交的时间段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Mathematical Biosciences and Engineering
Mathematical Biosciences and Engineering 工程技术-数学跨学科应用
CiteScore
3.90
自引率
7.70%
发文量
586
审稿时长
>12 weeks
期刊介绍: Mathematical Biosciences and Engineering (MBE) is an interdisciplinary Open Access journal promoting cutting-edge research, technology transfer and knowledge translation about complex data and information processing. MBE publishes Research articles (long and original research); Communications (short and novel research); Expository papers; Technology Transfer and Knowledge Translation reports (description of new technologies and products); Announcements and Industrial Progress and News (announcements and even advertisement, including major conferences).
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