Spot-stent grafting revisited - mid-term results of the treatment of Stanford type B aortic dissection and intramural haematoma.

IF 3.4 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE
Matthias Niklas Hagedorn, Moritz Sebastian Bischoff, Denis Skrypnik, Andreas Sebastian Peters, Dittmar Böckler, Katrin Meisenbacher
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引用次数: 0

Abstract

Background: Spot-stent grafting (SSG) for acute/subacute Stanford type B aortic dissection (ADB) and intramural hematoma (IMHB) entails selective coverage of the primary tear in the distal thoracic aorta (zones 4 or 5), with the stent graft fully deployed within the dissected segment-an intentional use beyond the Instructions for Use (IFU) aimed at minimising aortic coverage and preserving spinal cord perfusion. While early outcomes were favourable, long-term data on durability and reintervention remain limited. Materials and methods: In a single-centre retrospective analysis, all patients with acute/subacute ADB or IMHB treated with SSG between 03/1997 and 08/2024 were evaluated. The primary endpoint was the cumulative incidence of reintervention using a competing risk model over a median follow-up of 6.9 years (range 1.7 months-16.9 years). Secondary endpoints included technical success, aortic remodeling (AR), and false lumen thrombosis (FLT). Results: Of 270 TEVAR-treated patients with ADB or IMHB, 30 (16 ADB, 14 IMHB) underwent SSG. The cumulative incidence of reintervention at 30 days, one year, and three years was 6.7%, 16.7%, and 20%, respectively. Technical success was 100% with no 30-day mortality, stroke, or spinal ischaemia. Limited FLT occurred in 29/30, complete AR in 22/30. Reinterventions (7/30-23.3%) were distal (4) or proximal (3) extensions. Six-year survival was 66.7%. Conclusions: SSG demonstrated perioperative safety and mid-term efficacy beyond the IFU. However, higher reintervention rates - mainly proximal or distal extensions - may be expected, reflecting a trade-off for enhanced spinal cord protection in distal thoracic lesions when applied in carefully selected patients.

点式支架移植治疗Stanford B型主动脉夹层和壁内血肿的中期结果。
背景:对于急性/亚急性Stanford B型主动脉夹层(ADB)和壁内血肿(IMHB),点支架移植(SSG)需要选择性覆盖远端胸主动脉(4区或5区)的原发性撕裂,支架完全部署在夹层内,这是一种超出使用说明书(IFU)的故意使用,旨在最大限度地减少主动脉覆盖并保持脊髓灌注。虽然早期结果是有利的,但关于持久性和再干预的长期数据仍然有限。材料和方法:在一项单中心回顾性分析中,对1997年3月至2024年8月期间接受SSG治疗的所有急性/亚急性ADB或IMHB患者进行了评估。主要终点是在中位随访6.9年(1.7个月-16.9年)期间使用竞争风险模型进行再干预的累积发生率。次要终点包括技术成功、主动脉重塑(AR)和假腔血栓形成(FLT)。结果:270例tevar治疗的ADB或IMHB患者中,30例(ADB 16例,IMHB 14例)行SSG。30天、1年和3年的再干预累计发生率分别为6.7%、16.7%和20%。技术成功率为100%,无30天死亡率、中风或脊髓缺血。29/30发生有限FLT, 22/30发生完全AR。再介入(7/30-23.3%)为远端(4)或近端(3)伸展。6年生存率为66.7%。结论:SSG的围手术期安全性和中期疗效优于IFU。然而,更高的再干预率-主要是近端或远端延伸-可能是预期的,这反映了在精心选择的患者中应用时,对远端胸椎病变增强脊髓保护的权衡。
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来源期刊
CiteScore
3.90
自引率
11.10%
发文量
61
审稿时长
1 months
期刊介绍: Vasa is the European journal of vascular medicine. It is the official organ of the German, Swiss, and Slovenian Societies of Angiology. The journal publishes original research articles, case reports and reviews on vascular biology, epidemiology, prevention, diagnosis, medical treatment and interventions for diseases of the arterial circulation, in the field of phlebology and lymphology including the microcirculation, except the cardiac circulation. Vasa combines basic science with clinical medicine making it relevant to all physicians interested in the whole vascular field.
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