¹⁸F-FDG-PET/MRI Demonstration of Extensive Spinal Cord Metastases in a Patient with Ovarian Carcinoma.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Molecular Imaging and Radionuclide Therapy Pub Date : 2026-06-04 Epub Date: 2026-03-06 DOI:10.4274/mirt.galenos.2026.83097

Cansu Güneren, Sertaç Asa, Haluk Burçak Sayman

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Abstract

Spinal cord involvement is a rare manifestation of metastatic ovarian carcinoma. We report a case of high-grade serous ovarian cancer initially diagnosed in 2020. After cytoreductive surgery and multiple chemotherapy regimens, the patient developed brain metastases followed by small hypermetabolic foci along the spinal canal detected on ¹⁸F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (¹⁸F-FDG PET/MRI). These lesions, primarily located in the cervical region, were confirmed by contrast-enhanced spinal MRI but were more clearly visualized on ¹⁸F-FDG PET/MRI. Intramedullary spinal cord metastases are extremely rare and often underdiagnosed. While MRI remains the standard for anatomical assessment, ¹⁸F-FDG PET/MRI demonstrated superior lesion detection and definition in this case. This highlights the potential of hybrid imaging for improved diagnostic sensitivity in patients with suspected central nervous system involvement.

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18F-FDG-PET/MRI显示卵巢癌患者脊髓广泛转移。

脊髓受累是转移性卵巢癌的罕见表现。我们报告一例高级别浆液性卵巢癌最初诊断于2020年。在细胞减少手术和多次化疗方案后，患者发生脑转移，随后在18f -氟脱氧葡萄糖正电子发射断层扫描/磁共振成像（18F-FDG PET/MRI）上检测到沿椎管的小高代谢灶。这些病变主要位于颈椎区域，通过增强脊髓MRI证实，但在18F-FDG PET/MRI上更清晰可见。髓内脊髓转移极为罕见，且常被误诊。虽然MRI仍然是解剖评估的标准，但18F-FDG PET/MRI在本病例中显示出优越的病变检测和定义。这突出了混合成像在提高疑似中枢神经系统受累患者的诊断敏感性方面的潜力。

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来源期刊

Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.