Association Between Pregnancy Hope and Premenstrual Dysphoric Disorder Among Female Workers: A Cross-Sectional Online Survey in Japan.

IF 1.9 Q3 NEUROSCIENCES

Neuropsychopharmacology Reports Pub Date : 2026-03-01 DOI:10.1002/npr2.70106

Yuka Ito, Natsu Sasaki, Yoshiaki Kanamori, Rikako Tsuji, Mako Iida, Kazuhiro Watanabe, Miho Egawa, Daisuke Nishi

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Abstract

Objectives: This cross-sectional study examined the association between pregnancy hope and premenstrual dysphoric disorder (PMDD) outcomes among full-time working women.

Methods: We analyzed an October 2023 survey of nulligravid women aged 20-44 years (N = 1947). PMDD diagnosis and symptom severity were assessed using a DSM-IV-based scale. Logistic and linear regression examined associations with pregnancy hope and tested interaction by marital status.

Results: PMDD prevalence was 5.4% with pregnancy hope and 4.8% without. Pregnancy hope was not associated with PMDD diagnosis (crude OR = 1.13, 95% CI: 0.71-1.80) and remained null after adjustment. Pregnancy hope was weakly associated with higher symptom scores (crude standardized β = 0.059, p = 0.009), persisting after adjustment. Interaction by marital status was not significant.

Conclusion: Among full-time workers, pregnancy hope was unrelated to PMDD diagnosis but was weakly associated with subthreshold symptom severity. Longitudinal studies that comprehensively assess multidimensional pregnancy intention, perceptions of menstruation, and work-related constraints are needed to clarify causal directionality and mechanisms.

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日本女工怀孕希望与经前焦虑症的关系：一项横断面在线调查。

目的：本横断面研究考察了全职工作女性怀孕希望与经前烦躁障碍（PMDD）结果之间的关系。方法：我们分析了2023年10月对20-44岁无孕妇女（N = 1947）的调查。经前抑郁诊断和症状严重程度采用基于dsm - iv的量表进行评估。逻辑回归和线性回归检验了与怀孕希望的关系，并测试了婚姻状况的相互作用。结果：有妊娠希望的经前不悦症患病率为5.4%，无妊娠希望的患病率为4.8%。妊娠希望与经前抑郁诊断无关（粗OR = 1.13, 95% CI: 0.71-1.80），调整后仍为零。妊娠希望与较高的症状评分呈弱相关（粗标准化β = 0.059, p = 0.009），调整后持续存在。婚姻状况的交互作用不显著。结论：在全职工作者中，怀孕希望与经前抑郁诊断无关，但与阈下症状严重程度呈弱相关。需要进行纵向研究，全面评估多维怀孕意愿、月经感知和工作相关的限制，以阐明因果关系和机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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