Dynamics of natural biological membranes: an NMR history.

IF 5 Q1 BIOPHYSICS

Biophysical reviews Pub Date : 2025-11-03 eCollection Date: 2025-12-01 DOI:10.1007/s12551-025-01375-x

Erick J Dufourc, Estelle Morvan

引用次数: 0

Abstract

Since the publication of the fluid mosaic model for membranes in 1972, numerous spectroscopic techniques, including solid-state NMR (ssNMR), have been developed to assess membrane fluidity. While model membranes made from synthetic lipids have been widely used, experiments on natural membranes have remained rare. The first demonstration that natural membranes had a micro-fluidity comparable to that of model membranes was published by Ian CP Smith's team in the 1970s. This article reviews the first and most recent ssNMR experiments aimed at studying the dynamics of natural membranes, as measured by order parameters, and their comparison with models.

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天然生物膜动力学：核磁共振历史。

自1972年膜的流体镶嵌模型发表以来，许多光谱技术，包括固态核磁共振（ssNMR），已经发展到评估膜流动性。虽然由合成脂质制成的模型膜已被广泛使用，但对天然膜的实验仍然很少。20世纪70年代，伊恩·CP·史密斯（Ian CP Smith）的团队首次证明了天然膜具有与模型膜相当的微流动性。本文回顾了第一次和最近的ssNMR实验，旨在研究天然膜的动力学，通过有序参数测量，并与模型进行比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biophysical reviews Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

8.90

自引率

0.00%

发文量

期刊介绍： Biophysical Reviews aims to publish critical and timely reviews from key figures in the field of biophysics. The bulk of the reviews that are currently published are from invited authors, but the journal is also open for non-solicited reviews. Interested authors are encouraged to discuss the possibility of contributing a review with the Editor-in-Chief prior to submission. Through publishing reviews on biophysics, the editors of the journal hope to illustrate the great power and potential of physical techniques in the biological sciences, they aim to stimulate the discussion and promote further research and would like to educate and enthuse basic researcher scientists and students of biophysics. Biophysical Reviews covers the entire field of biophysics, generally defined as the science of describing and defining biological phenomenon using the concepts and the techniques of physics. This includes but is not limited by such areas as: - Bioinformatics - Biophysical methods and instrumentation - Medical biophysics - Biosystems - Cell biophysics and organization - Macromolecules: dynamics, structures and interactions - Single molecule biophysics - Membrane biophysics, channels and transportation