{"title":"Colistin-Associated Acute Kidney Injury in Burn Patients: Incidence, Associated Factors and Prognosis.","authors":"S Ben Massoud, H Fredj, A Mokline, A A Messadi","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Colistin is often essential in burn patients presenting infections caused by multidrug-resistant organisms. A retrospective study was conducted in the intensive burn care department in Tunisia over 14 months to assess prevalence and predictive factors of colistin-related acute kidney injury (AKI). Among 70 patients (mean age 34±13 years), 28.6% developed AKI, with onset at 5±2 days. Associated factors included total burned surface area >41% (OR=2.6), UBS score >58 (OR=6.8), metabolic acidosis at admission (OR=28) and contrast agent injection (OR=107). AKI was reversible in 40% of cases. Colistin-associated AKI remains a frequent complication in severely burned patients, and in cases of contrast agent use.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"39 1","pages":"63-69"},"PeriodicalIF":0.0000,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954713/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of burns and fire disasters","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Colistin is often essential in burn patients presenting infections caused by multidrug-resistant organisms. A retrospective study was conducted in the intensive burn care department in Tunisia over 14 months to assess prevalence and predictive factors of colistin-related acute kidney injury (AKI). Among 70 patients (mean age 34±13 years), 28.6% developed AKI, with onset at 5±2 days. Associated factors included total burned surface area >41% (OR=2.6), UBS score >58 (OR=6.8), metabolic acidosis at admission (OR=28) and contrast agent injection (OR=107). AKI was reversible in 40% of cases. Colistin-associated AKI remains a frequent complication in severely burned patients, and in cases of contrast agent use.
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