Megan E Patrick, Yuk C Pang, Yvonne M Terry-McElrath, Joy Bohyun Jang
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引用次数: 0
Abstract
ObjectivesWe examined longitudinal associations between young adult heavy substance use and late midlife poor self-rated memory and whether problematic substance use in early midlife mediated the associations.MethodsData were from the Monitoring the Future Longitudinal Panel Study. Analyses included individuals ages 50-65 in 2018-2023 who provided longitudinal data starting at age 18 in 1976-1991.ResultsYoung adult heavy use of all substances was directly associated with higher odds of late midlife poor self-rated memory. These associations were fully mediated by early midlife substance-use disorder symptoms for binge drinking and cannabis use, but not mediated for pack+/day cigarette smoking.DiscussionSustained heavy substance use in young adulthood appears to represent a cumulative risk factor for cognitive decline in late midlife. Examining risk factors, including substance use, across the life course may be crucial for earlier identification of risk for cognitive decline.
期刊介绍：
The Journal of Aging and Health is an interdisciplinary forum for the presentation of research findings and scholarly exchange in the area of aging and health. Manuscripts are sought that deal with social and behavioral factors related to health and aging. Disciplines represented include the behavioral and social sciences, public health, epidemiology, demography, health services research, nursing, social work, medicine, and related disciplines. Although preference is given to manuscripts presenting the findings of original research, review and methodological pieces will also be considered.
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