Comparative Outcomes and Efficacy of Programmable Versus Nonprogrammable Ventriculoperitoneal Shunts in the Management of Normal Pressure Hydrocephalus: A Retrospective Study.
Sultan Jarrar, Mohammed M Al Barbarawi, Amer Jaradat, Suleiman S Daoud, Atef F Hulliel, Teeba Mubaydeen, Sa'ed Hasan, Hamzeh Moh'd Marzouq Bakhiet, Abdulhakim Aldaoud, Adam Abdallah
{"title":"Comparative Outcomes and Efficacy of Programmable Versus Nonprogrammable Ventriculoperitoneal Shunts in the Management of Normal Pressure Hydrocephalus: A Retrospective Study.","authors":"Sultan Jarrar, Mohammed M Al Barbarawi, Amer Jaradat, Suleiman S Daoud, Atef F Hulliel, Teeba Mubaydeen, Sa'ed Hasan, Hamzeh Moh'd Marzouq Bakhiet, Abdulhakim Aldaoud, Adam Abdallah","doi":"10.1155/nri/8882884","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Normal pressure hydrocephalus (NPH) is a neurological disorder in older adults, characterized by gait disturbance, urinary incontinence, and cognitive impairment, along with ventriculomegaly and normal intracranial pressure. The management of NPH often involves ventriculoperitoneal shunting (VPS), which can be programmable (P-VPS) or nonprogrammable (NP-VPS). While P-VPS offers the advantage of adjustable pressure settings, its impact on clinical outcomes and complications remains debated, particularly in resource-limited settings like Jordan.</p><p><strong>Method: </strong>A retrospective review was conducted of 38 adult patients diagnosed with idiopathic NPH who underwent VPS placement between 2018 and 2024. Patients were classified into two groups: P-VPS and NP-VPS. Clinical outcomes, including symptom improvement, complication rates, hospital stay duration, and shunt revisions, were analyzed. Statistical comparisons were made using SPSS, with <i>p</i> values < 0.05 considered significant.</p><p><strong>Results: </strong>The study found no significant differences between the two groups in symptom improvement. However, the NP-VPS group had a significantly shorter hospital stay (5.7 ± 3.2 days vs. 14.1 ± 11.9 days, <i>p</i> = 0.007). Complication rates, including infection and shunt revision, were higher in the P-VPS group (20.0% vs. 7.7% for infection; 32.0% vs. 15.4% for revision), though differences were not statistically significant.</p><p><strong>Conclusion: </strong>Both P-VPS and NP-VPS resulted in similar symptom improvements, with NP-VPS showing a trend toward shorter hospital stays and comparable complication rates. Further multicenter studies with larger sample sizes are needed to validate these findings and refine management strategies for NPH.</p>","PeriodicalId":19124,"journal":{"name":"Neurology Research International","volume":"2026 ","pages":"8882884"},"PeriodicalIF":2.8000,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12951206/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurology Research International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/nri/8882884","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Normal pressure hydrocephalus (NPH) is a neurological disorder in older adults, characterized by gait disturbance, urinary incontinence, and cognitive impairment, along with ventriculomegaly and normal intracranial pressure. The management of NPH often involves ventriculoperitoneal shunting (VPS), which can be programmable (P-VPS) or nonprogrammable (NP-VPS). While P-VPS offers the advantage of adjustable pressure settings, its impact on clinical outcomes and complications remains debated, particularly in resource-limited settings like Jordan.
Method: A retrospective review was conducted of 38 adult patients diagnosed with idiopathic NPH who underwent VPS placement between 2018 and 2024. Patients were classified into two groups: P-VPS and NP-VPS. Clinical outcomes, including symptom improvement, complication rates, hospital stay duration, and shunt revisions, were analyzed. Statistical comparisons were made using SPSS, with p values < 0.05 considered significant.
Results: The study found no significant differences between the two groups in symptom improvement. However, the NP-VPS group had a significantly shorter hospital stay (5.7 ± 3.2 days vs. 14.1 ± 11.9 days, p = 0.007). Complication rates, including infection and shunt revision, were higher in the P-VPS group (20.0% vs. 7.7% for infection; 32.0% vs. 15.4% for revision), though differences were not statistically significant.
Conclusion: Both P-VPS and NP-VPS resulted in similar symptom improvements, with NP-VPS showing a trend toward shorter hospital stays and comparable complication rates. Further multicenter studies with larger sample sizes are needed to validate these findings and refine management strategies for NPH.
背景：常压脑积水（NPH）是一种老年人神经系统疾病，其特征是步态障碍、尿失禁和认知障碍，同时伴有脑室肿大和颅内压正常。NPH的治疗通常涉及脑室-腹膜分流术（VPS），可编程（P-VPS）或不可编程（NP-VPS）。虽然P-VPS具有可调节压力设置的优势，但其对临床结果和并发症的影响仍存在争议，特别是在约旦等资源有限的地区。方法：对2018年至2024年间接受VPS置入术的38例特发性NPH成年患者进行回顾性分析。患者分为两组：P-VPS和NP-VPS。分析临床结果，包括症状改善、并发症发生率、住院时间和分流修复。采用SPSS软件进行统计学比较，p值为p值。结果：研究发现两组患者在症状改善方面无显著差异。然而，NP-VPS组的住院时间明显缩短（5.7±3.2天比14.1±11.9天，p = 0.007）。P-VPS组的并发症发生率，包括感染和分流管翻修，更高（感染20.0% vs. 7.7%；翻修32.0% vs. 15.4%），但差异无统计学意义。结论：P-VPS和NP-VPS的症状改善相似，NP-VPS的住院时间更短，并发症发生率相当。进一步的多中心研究需要更大的样本量来验证这些发现，并完善NPH的管理策略。
期刊介绍：
Neurology Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focusing on diseases of the nervous system, as well as normal neurological functioning. The journal will consider basic, translational, and clinical research, including animal models and clinical trials.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
