Sun Hyun Chang, Malathy Palayam, Katherine A Hand, Nitzan Shabek
{"title":"Structural Insights into Plant Hormone-Sensing Mechanisms.","authors":"Sun Hyun Chang, Malathy Palayam, Katherine A Hand, Nitzan Shabek","doi":"10.1146/annurev-arplant-060625-095356","DOIUrl":null,"url":null,"abstract":"<p><p>Plant hormones are essential small molecules that regulate plant growth, development, and systemic responses to environmental stimuli. These processes are mediated by complex signaling networks involving structurally diverse receptors, regulatory proteins, and dynamic protein-protein interactions. Advances in structural and functional biology over the past two decades have revealed how hormone receptors recognize their ligands and how they mediate responses from perception to signaling through transduction pathways and feedback regulation. In this review, we summarize the current knowledge of plant hormone receptors with experimentally determined structures and highlight their central roles in shaping plant biology. Finally, we discuss outstanding questions in the field and how emerging computational tools may help address these gaps.</p>","PeriodicalId":8335,"journal":{"name":"Annual review of plant biology","volume":" ","pages":"319-350"},"PeriodicalIF":26.4000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annual review of plant biology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1146/annurev-arplant-060625-095356","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/3 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Plant hormones are essential small molecules that regulate plant growth, development, and systemic responses to environmental stimuli. These processes are mediated by complex signaling networks involving structurally diverse receptors, regulatory proteins, and dynamic protein-protein interactions. Advances in structural and functional biology over the past two decades have revealed how hormone receptors recognize their ligands and how they mediate responses from perception to signaling through transduction pathways and feedback regulation. In this review, we summarize the current knowledge of plant hormone receptors with experimentally determined structures and highlight their central roles in shaping plant biology. Finally, we discuss outstanding questions in the field and how emerging computational tools may help address these gaps.
期刊介绍:
The Annual Review of Plant Biology is a peer-reviewed scientific journal published by Annual Reviews. It has been in publication since 1950 and covers significant developments in the field of plant biology, including biochemistry and biosynthesis, genetics, genomics and molecular biology, cell differentiation, tissue, organ and whole plant events, acclimation and adaptation, and methods and model organisms. The current volume of this journal has been converted from gated to open access through Annual Reviews' Subscribe to Open program, with all articles published under a CC BY license.