Synthesis of Submicron Particles of the Boron-10 Isotope by Mechanical Milling in Planetary Ball Mills

IF 0.8 Q3 Engineering

Nanotechnologies in Russia Pub Date : 2026-03-02 DOI:10.1134/S2635167625602001

A. A. Fronya, K. O. Fomin, K. S. Pervakov, I. M. Tupitsyn, E. I. Mavreshko, D. S. Petrunya, M. S. Grigoryeva, E. V. Barmina, I. N. Zavestovskaya

引用次数: 0

Abstract

One promising application of nuclear-physics methods in medicine is boron neutron capture therapy (BNCT). A key aspect of the effectiveness of BNCT is the production of boron-containing materials with the required concentration and the ability to keep the drug within the tumor. This work presents the results of the initial stage of boron-10 nanoparticle synthesis, which includes the synthesis of submicron particles by milling boron-10 in a planetary ball mill. Solutions of boron-10 in isopropanol with submicron particle sizes of 150–600 nm are obtained. The optimal milling conditions are determined to ensure the required boron-10 concentration and minimize the presence of impurities.

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行星球磨机机械磨合成硼-10同位素亚微米颗粒

核物理方法在医学上的一个很有前景的应用是硼中子俘获治疗（BNCT）。BNCT有效性的一个关键方面是产生具有所需浓度的含硼材料，并能够将药物保持在肿瘤内。这项工作介绍了硼-10纳米颗粒合成的初始阶段的结果，其中包括通过在行星球磨机中研磨硼-10合成亚微米颗粒。在异丙醇中得到了颗粒尺寸为150 ~ 600nm的亚微米级硼-10溶液。确定了最佳的研磨条件，以确保所需的硼-10浓度，并尽量减少杂质的存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.