Genome-Wide Association Analysis of Pathologies in Piglets of Landrace and Large White Breeds

IF 0.8 Q3 Engineering

Nanotechnologies in Russia Pub Date : 2026-03-02 DOI:10.1134/S2635167625601652

E. D. Solovkova, V. S. Bezuglov, A. A. Borisova, A. A. Frolova, A. V. Prokopenko, S. S. Bulanov, A. E. Sazonov, M. V. Patrushev

引用次数: 0

Abstract

A genome-wide association study is conducted to identify gene polymorphisms in pigs associated with common pathologies in young animals. The genomes of 97 pigs (Landrace and Large White breeds) are sequenced, followed by genome-wide association analysis to identify possible markers of potentially heritable defects (malnutrition, gastroenteritis, scrotal hernia and cryptorchidism, tremors at birth). Polymorphisms are found in various genes, including those associated with development of the nervous system and the formation of neurological diseases, even in the case of pathologies not directly related to the functions of the nervous system.

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长白猪与大白仔猪病理的全基因组关联分析

进行了一项全基因组关联研究，以确定猪中与幼龄动物常见疾病相关的基因多态性。对97头猪（长白猪和大白猪）的基因组进行测序，然后进行全基因组关联分析，以确定潜在遗传缺陷（营养不良、肠胃炎、阴囊疝和隐睾、出生时震颤）的可能标记。在各种基因中发现多态性，包括与神经系统发育和神经疾病形成有关的基因，甚至在与神经系统功能没有直接关系的病理情况下也是如此。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.