Glutathione and Magnetic Nanoparticle-Modified Nanochannels for the Detection of Cadmium (II) in Cereal Grains

IF 2.8 4区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Magnetochemistry Pub Date : 2025-07-21 DOI:10.3390/magnetochemistry11070061

Wei Hu, Xinyue Xiang, Donglei Jiang, Na Zhang, Lifeng Wang

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引用次数: 0

Abstract

We developed a novel and portable magnetic nanochannel electrochemical sensor for the sensitive detection of cadmium ions (Cd2+), which pose serious risks to food safety and human health. The sensor was fabricated by co-modifying an anodic aluminum oxide (AAO) nanochannel membrane with a composite of glutathione (GSH) and ferric oxide nanoparticles (Fe3O4), denoted as GSH@Fe3O4. This modified membrane was then integrated with a screen-printed carbon electrode (SPCE) to construct the GSH@Fe3O4/GSH@AAO/SPCE sensing platform. The performance of the sensor was evaluated using differential pulse voltammetry (DPV), which demonstrated a strong linear correlation between the peak current response and the concentration of Cd2+ in the range of 5–120 μg/L. The calibration equation was IDPV(μA) = −0.31 + 0.98·CCd2+(μg/L), with an excellent correlation coefficient (R2 = 0.999, n = 3). The calculated limit of detection (LOD) was as low as 0.1 μg/L, indicating the high sensitivity of the system. These results confirm the successful construction of the GSH@Fe3O4/GSH@AAO/SPCE portable nanochannel sensor. This innovative sensing platform provides a rapid, sensitive, and user-friendly approach for the on-site monitoring of heavy metal contamination in agricultural products, especially grains.

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谷胱甘肽和磁性纳米粒子修饰纳米通道检测谷物中镉（II）

本文研制了一种新型的便携式磁性纳米通道电化学传感器，用于灵敏检测镉离子（Cd2+），这对食品安全和人类健康构成严重威胁。该传感器是用谷胱甘肽（GSH）和氧化铁纳米颗粒（Fe3O4）共改性阳极氧化铝（AAO）纳米通道膜制成的，标记为GSH@Fe3O4。然后将该改性膜与丝网印刷碳电极（SPCE）集成，构建GSH@Fe3O4/GSH@AAO/SPCE传感平台。采用差分脉冲伏安法（DPV）对传感器的性能进行了评价，结果表明，在5 ~ 120 μg/L范围内，峰值电流响应与Cd2+浓度呈较强的线性相关。标定方程为IDPV(μA) = - 0.31 + 0.98·CCd2+(μ L)，相关系数R2 = 0.999, n = 3。计算检出限（LOD）低至0.1 μg/L，表明该系统具有较高的灵敏度。这些结果证实了GSH@Fe3O4/GSH@AAO/SPCE便携式纳米通道传感器的成功构建。这种创新的传感平台为现场监测农产品特别是谷物中的重金属污染提供了一种快速、灵敏、用户友好的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Magnetochemistry Chemistry-Chemistry (miscellaneous)

CiteScore

3.90

自引率

11.10%

发文量

145

审稿时长

11 weeks

期刊介绍： Magnetochemistry (ISSN 2312-7481) is a unique international, scientific open access journal on molecular magnetism, the relationship between chemical structure and magnetism and magnetic materials. Magnetochemistry publishes research articles, short communications and reviews. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.