A Novel Procedure for Treating Parenteral Nutrition-Induced Occlusion of a Single-Lumen Peripherally Inserted Central Catheter.

IF 1.2 Q1 NURSING

Journal of Infusion Nursing Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI:10.1097/NAN.0000000000000633

Hong Li, Jishi Li, Jinliang Zhang, Jiandong Zha, Yiping Tang, Xian Chen

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引用次数: 0

Abstract

Objective: The aim of the study was to evaluate the effectiveness of replacing the connector assembly in resolving occlusion of peripherally inserted central catheters (PICCs) during parenteral nutrition (PN) administration.

Methods: This retrospective study reviewed data from 24 patients who received PN via 4Fr single-lumen silicone PICCs at a 2000-bed tertiary general hospital between 2018 and 2023. All patients experienced either partial or complete catheter occlusion following PN infusion. A novel procedure was adopted to replace the connector assembly, and the subsequent outcomes were observed.

Results: The success rates of connector replacement were 87.5% and 50.0% on the first and second attempts, respectively, with restored catheter function. Repeated replacement, however, markedly reduced patency (from 87.5% to 0% after the third replacement) and progressively shortened the median functional indwelling time (from 44.5 to 36.5 days), indicating diminished overall durability and therapeutic efficacy.

Conclusion: Connector assembly replacement is an effective, immediate, and economical method to resolve PICC occlusions caused by PN. This approach may offer a practical alternative to chemical catheter clearance, particularly for 4Fr single-lumen silicone catheters.

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一种治疗肠外营养引起的单腔外周中心导管阻塞的新方法。

目的：本研究的目的是评估更换连接器组件在解决肠外营养（PN）管理期间外周插入中心导管（PICCs）闭塞的有效性。方法：本回顾性研究回顾了2018年至2023年在一家2000张床位的三级综合医院通过4Fr单腔硅胶PICCs接受PN治疗的24例患者的数据。所有患者在PN输注后都经历了部分或完全的导管阻塞。采用了一种新的方法来更换连接器组件，并观察了随后的结果。结果：第一次和第二次更换导管接头的成功率分别为87.5%和50.0%，导管功能恢复。然而，反复更换明显降低了通畅度（从第三次更换后的87.5%降至0%），并逐渐缩短了中位功能留置时间（从44.5天降至36.5天），表明总体持久性和治疗效果下降。结论：置换术是一种有效、快速、经济的治疗PN所致PICC闭塞的方法。这种方法可能为化学导管清除提供了一种实用的替代方法，特别是对于4Fr单腔硅胶导管。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Infusion Nursing NURSING-

CiteScore

4.00

自引率

15.00%

发文量

期刊介绍： Journal of Infusion Nursing, the official publication of the Infusion Nurses Society (INS), seeks to promote excellence in infusion nursing by presenting new research, clinical reviews, case studies, and professional development information relevant to the practice of infusion therapy. Articles selected for publication represent the broad scope of the infusion specialty and draw on the expertise of all healthcare providers who participate in the delivery of infusion therapy.