Marvin A Simpkins, Garrett Douglas, Dominic M Collins, Aishniya Kandula, Darshan Sangani, Roger Robertson
{"title":"A Rare Paratesticular Leiomyosarcoma Presenting as a Painless Scrotal Mass in an Elderly Patient: A Case Report.","authors":"Marvin A Simpkins, Garrett Douglas, Dominic M Collins, Aishniya Kandula, Darshan Sangani, Roger Robertson","doi":"10.1177/23247096261420891","DOIUrl":null,"url":null,"abstract":"<p><p>Leiomyosarcomas (LMS) are malignant tumors originating from smooth muscle and rarely found in the scrotum. LMS has an insidious presentation that is often misdiagnosed as a benign lesion. This report outlines an innocuous case of paratesticular leiomyosarcoma while focusing on the diagnosis and treatment paratesticular LMS. We report the case of an 84-year-old male who presented with a painless left scrotal swelling of 5 days' duration. Imaging and tumor markers suggested a paratesticular mass suspicious for malignancy. Surgical excision revealed a Fédération Nationale des Centres de Lutte Contre le Cancer Grade 2 leiomyosarcoma arising from the scrotal soft tissue, confirmed by positive smooth muscle markers on immunohistochemistry. Postoperative imaging demonstrated no recurrence at 8 months. This case highlights the diagnostic challenge of paratesticular leiomyosarcoma and the importance of surgical resection and careful follow-up for optimal patient outcomes.</p>","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":"14 ","pages":"23247096261420891"},"PeriodicalIF":0.7000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12936359/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of investigative medicine high impact case reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/23247096261420891","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Leiomyosarcomas (LMS) are malignant tumors originating from smooth muscle and rarely found in the scrotum. LMS has an insidious presentation that is often misdiagnosed as a benign lesion. This report outlines an innocuous case of paratesticular leiomyosarcoma while focusing on the diagnosis and treatment paratesticular LMS. We report the case of an 84-year-old male who presented with a painless left scrotal swelling of 5 days' duration. Imaging and tumor markers suggested a paratesticular mass suspicious for malignancy. Surgical excision revealed a Fédération Nationale des Centres de Lutte Contre le Cancer Grade 2 leiomyosarcoma arising from the scrotal soft tissue, confirmed by positive smooth muscle markers on immunohistochemistry. Postoperative imaging demonstrated no recurrence at 8 months. This case highlights the diagnostic challenge of paratesticular leiomyosarcoma and the importance of surgical resection and careful follow-up for optimal patient outcomes.
期刊介绍:
The AFMR is committed to enhancing the training and career development of our members and to furthering its mission to facilitate the conduct of research to improve medical care. Case reports represent an important avenue for trainees (interns, residents, and fellows) and early-stage faculty to demonstrate productive, scholarly activity.