Ability of the continuous carotid Doppler patch to track directional changes in cardiac output in cardiac surgery patients.

IF 4.8 3区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

European Journal of Medical Research Pub Date : 2026-02-24 DOI:10.1186/s40001-026-04034-3

Guang-Wei Hao, Dan-Lei Huang, Guo-Guang Ma, Ying Su, Jun-Yi Hou, Yi-Jie Zhang, Wen-Jun Liu, Zhi-Hui Lu, Zhe Luo, Guo-Wei Tu

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引用次数: 0

Abstract

Background: Hands-free patch for continuous quantitative monitoring of common carotid artery (CCA) blood flow has gained interest in recent years. The aim of this study was to evaluate whether carotid minute distance (cMD), collected from a hands-free continuous wave Doppler, allows tracking directional changes incardiac output (CO) induced by passive leg raising (PLR) or dobutamine test in cardiac surgery patients.

Methods: Cardiac surgery patients with pulmonary artery catheter or transpulmonary thermodilution monitoring were enrolled. Four-quadrant plot was adopted to evaluate the concordance between the percentage change of CCA cMD, which was the product of heart rate and velocity time integral, and invasive CO induced by PLR or dobutamine test.

Results: A total of 41 cardiac surgery patients were enrolled and 82 pairs of invasive CO and cMD induced by the PLR or dobutamine test were collected in this study. Following the PLR test, significant increases were observed in CO (5.3 ± 1.1 vs. 5.7 ± 1.3 L/min, p﹤0.001). Similarly, dobutamine administration resulted in marked elevations of CO (5.3 ± 1.1 vs. 6.0 ± 1.3 L/min, p﹤0.001). Compared with baseline values, cMD demonstrated significant enhancement following both PLR test and dobutamine challenge. The concordance rate between percentage change of CO and cMD was 98.5%, with the coefficient of determination (R²) be 0.58 (p﹤0.001).

Conclusions: In cardiac surgery patients, cMD collected from a hands-free CADFlow monitor system could reliably tracking directional changes of CO, with thermodilution technique be the reference method.

Trial registration: ClinicalTrials.gov (NCT05944146). Registered July 12, 2023.

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连续颈动脉多普勒贴片追踪心脏手术患者心输出量方向变化的能力。

背景：用于连续定量监测颈总动脉（CCA）血流的免提贴片近年来引起了人们的兴趣。本研究的目的是评估颈动脉分钟距离（cMD）是否可以跟踪心脏手术患者被动抬腿（PLR）或多巴酚丁胺试验引起的心输出量（CO）的方向变化。方法：采用经肺动脉导管或经肺热稀释监测的心脏手术患者。采用四象限图评价心率与速度时间积分乘积CCA cMD百分比变化与PLR或多巴酚丁胺试验所致有创性CO的一致性。结果：本研究共纳入41例心脏手术患者，共收集到PLR或多巴酚丁胺试验诱发的有创性CO和cMD 82对。PLR试验后，CO显著升高（5.3±1.1 vs. 5.7±1.3 L/min, p<0.001）。同样，多巴酚丁胺处理导致CO显著升高（5.3±1.1 vs. 6.0±1.3 L/min, p<0.001）。与基线值相比，cMD在PLR测试和多巴酚丁胺刺激后均表现出显著增强。CO变化百分比与cMD的符合率为98.5%，决定系数（R2）为0.58 （p<0.001）。结论：在心脏手术患者中，免持式CADFlow监测系统采集的cMD可可靠地跟踪CO的方向变化，热稀释技术可作为参考方法。试验注册：ClinicalTrials.gov （NCT05944146）。2023年7月12日注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Medical Research 医学-医学：研究与实验

CiteScore

3.20

自引率

0.00%

发文量

247

审稿时长

>12 weeks

期刊介绍： European Journal of Medical Research publishes translational and clinical research of international interest across all medical disciplines, enabling clinicians and other researchers to learn about developments and innovations within these disciplines and across the boundaries between disciplines. The journal publishes high quality research and reviews and aims to ensure that the results of all well-conducted research are published, regardless of their outcome.